120693
α-Methyl-DL-tyrosine
98%
Synonym(s):
DL-2-Methyl-3-(4-hydroxyphenyl)alanine, AMPT
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About This Item
Linear Formula:
4-(HO)C6H4CH2C(CH3)(NH2)CO2H
CAS Number:
Molecular Weight:
195.22
EC Number:
211-523-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
2938704
MDL number:
InChI key
NHTGHBARYWONDQ-UHFFFAOYSA-N
InChI
1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)
SMILES string
CC(N)(Cc1ccc(O)cc1)C(O)=O
assay
98%
form
powder
reaction suitability
reaction type: solution phase peptide synthesis
technique(s)
HPLC: suitable
color
white to off-white
mp
>300 °C (lit.)
application(s)
peptide synthesis
Gene Information
human ... TH(7054)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Joram D Mul et al.
PloS one, 8(3), e60214-e60214 (2013-04-05)
The orexigenic neuropeptide melanin-concentrating hormone (MCH), a product of Pmch, is an important mediator of energy homeostasis. Pmch-deficient rodents are lean and smaller, characterized by lower food intake, body-, and fat mass. Pmch is expressed in hypothalamic neurons that ultimately
Khoa D Nguyen et al.
Nature, 480(7375), 104-108 (2011-11-22)
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Maria Xilouri et al.
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The mechanisms through which aberrant alpha-synuclein (ASYN) leads to neuronal death in Parkinson's disease (PD) are uncertain. In isolated liver lysosomes, mutant ASYNs impair Chaperone Mediated Autophagy (CMA), a targeted lysosomal degradation pathway; however, whether this occurs in a cellular
Kinuyo Iwata et al.
The Journal of reproduction and development, 57(3), 379-384 (2011-03-02)
Ketosis is found in various pathophysiological conditions, including diabetes and starvation, that are accompanied by suppression of gonadal activity. The aim of the present study was to determine the role of ketone body in the brain in regulating pulsatile luteinizing
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