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Merck
CN

121967

Aminoacetaldehyde dimethyl acetal

99%

Synonym(s):

2,2-Dimethoxyethylamine

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About This Item

Linear Formula:
NH2CH2CH(OCH3)2
CAS Number:
Molecular Weight:
105.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
245-026-5
Beilstein/REAXYS Number:
741868
MDL number:
Assay:
99%
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Quality Segment

assay

99%

refractive index

n20/D 1.417 (lit.)

bp

135-139 °C/95 mmHg (lit.)

density

0.965 g/mL at 25 °C (lit.)

functional group

acetal, amine, ether

SMILES string

COC(CN)OC

InChI

1S/C4H11NO2/c1-6-4(3-5)7-2/h4H,3,5H2,1-2H3

InChI key

QKWWDTYDYOFRJL-UHFFFAOYSA-N

General description

Aminoacetaldehyde dimethyl acetal reacts with sulfone, followed by hydrolysis and reductive amination by adding desired piperazine derivative to yield piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine.

Aminoacetaldehyde dimethyl acetal is used as a building block for the synthesis of various acylated and sufonylated oxyenamides.

Application

Aminoacetaldehyde dimethyl acetal was used in a study to develop a fluorescent substrate for aldehyde dehydrogenase. It was used in preparation of chitosan-dendrimer hybrids having various functional groups such as carboxyl, ester and poly(ethylene glycol). It was used in an efficient 3-step synthesis of a bicyclic proline analog from L-ascorbic acid and in 3-component reaction catalyzed by MgClO4 leading to α-aminophosphonates.


pictograms

FlameCorrosion

signalword

Danger

hcodes

Hazard Classifications

Flam. Liq. 3 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

111.2 °F - closed cup

flash_point_c

44 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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