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Merck
CN

124192

1,4-Butanediol diglycidyl ether

technical grade, 60%

Synonym(s):

1,4-Bis(2,3-epoxypropoxy)butane, 1,4-Bis(glycidyloxy)butane, 1,4-Bis(oxiran-2-ylmethoxy)butane, 1,4-Butylene glycol diglycidyl ether, Tetramethylene glycol diglycidyl ether

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About This Item

Empirical Formula (Hill Notation):
C10H18O4
CAS Number:
2425-79-8
Molecular Weight:
202.25
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
24847603
EC Number:
219-371-7
Beilstein/REAXYS Number:
115238
MDL number:
MFCD00005146

Key Documents

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Product Name

1,4-Butanediol diglycidyl ether, technical grade, 60%

InChI key

SHKUUQIDMUMQQK-UHFFFAOYSA-N

InChI

1S/C10H18O4/c1(3-11-5-9-7-13-9)2-4-12-6-10-8-14-10/h9-10H,1-8H2

SMILES string

C(CCOCC1CO1)COCC2CO2

grade

technical grade

vapor pressure

~10 mmHg ( 20 °C)

form

liquid

concentration

60%

refractive index

n20/D 1.453 (lit.)

bp

266 °C (lit.)

density

1.1 g/mL at 25 °C (lit.)

Quality Level

200

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Application

1,4-Butanediol diglycidyl ether can be used:
  • As a cross-linking agent to prepare hyaluronic acid dermal fillers This crosslinking process enhances the gel-like consistency of the filler, making it more durable and longer-lasting.
  • As a monomer to prepare epoxy-based graphene nanocomposites that have potential applications in the field of flexible electronics, corrosion resistance coatings, and conductive adhesives. BDDE is chosen for its desirable properties such as low viscosity, good reactivity, and compatibility with graphene.

General description

1,4-Butanediol diglycidyl ether(BDDE) is a homobifunctional monomer with two epoxide groups, widely used to modify the viscosity of epoxy resins. It is also used as a cross-linking agent to synthesize polymer networks.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ4956
MKCZ3278
MKCX8695
MKCX8320
MKCX8322

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Comparative physicochemical analysis among 1, 4-butanediol diglycidyl ether cross-linked hyaluronic acid dermal fillers
Nicola Zerbinati, et al.
Gels, 7, 139-139 (2021)
Cheng Chen et al.
Biotechnology and applied biochemistry, 45(Pt 2), 87-92 (2006-05-25)
At present, the common tool for affinity purification of IgG is immobilized Protein A, which is separated from native cell-wall components of Staphylococcus aureus. It is complicated and costly to prepare natural Protein A. ZZ protein is a synthetic Fc
M P Markowicz et al.
The International journal of artificial organs, 29(12), 1167-1173 (2007-01-16)
Ongoing research has achieved much progress towards the development of new artificial skin substitute products. However, effective implant material for correcting full-thickness defects (such as those arising from extensive burns, tumor resection, hereditary or congenital defects and chronic wounds) has
Anabela Alves et al.
International journal of pharmaceutics, 426(1-2), 76-81 (2012-01-28)
The polysaccharide ulvan, composed of sulphated rhamnose, glucoronic and iduronic acids was used to produce polymeric membranes by solvent casting. As ulvan is soluble in water, a cross-linking step was necessary to render the membrane insoluble in water and stable
R Zeeman et al.
Journal of biomedical materials research, 46(3), 424-433 (1999-07-09)
Crosslinking of dermal sheep collagen (DSC) was accomplished using 1, 4-butanediol diglycidyl ether (BDDGE). At pH values > 8.0, epoxide groups of BDDGE will react with amine groups of collagen. The effects of BDDGE concentration, pH, time, and temperature were
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