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Merck
CN

125598

Sigma-Aldrich

1,4-Cyclohexanedimethanol

mixture of cis and trans, 99%

Synonym(s):

1,4-Bis(hydroxymethyl)cyclohexane, mixture of cis and trans

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About This Item

Linear Formula:
C6H10(CH2OH)2
CAS Number:
Molecular Weight:
144.21
Beilstein:
1902271
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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vapor density

5 (vs air)

Quality Level

Assay

99%

autoignition temp.

584 °F

bp

283 °C (lit.)

functional group

hydroxyl

SMILES string

OCC1CCC(CO)CC1

InChI

1S/C8H16O2/c9-5-7-1-2-8(6-10)4-3-7/h7-10H,1-6H2

InChI key

YIMQCDZDWXUDCA-UHFFFAOYSA-N

General description

1,4-Cyclohexanedimethano is extensively used as cross-linking reagent in polymer industry.

Application

1,4-Cyclohexanedimethanol has been used in the synthesis of polyketal copolymers. It was used as diol comonomer during the synthesis of polyester-carbonates based on 1,3-propylene-co-1,4-cyclohexanedimethylene succinate.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

321.8 °F - closed cup

Flash Point(C)

161 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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New biodegradable polymers from renewable sources: Polyester-carbonates based on 1, 3-propylene-co-1, 4-cyclohexanedimethylene succinate.
Liu Y, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 39(14), 2508-2519 (2001)
Mingliang Ding et al.
Biodegradation, 23(1), 127-132 (2011-07-07)
Enzymatic hydrolytic degradation of polybutylene succinate (PBS), poly(polybutylenesuccinate-co-1,4-cyclohexane dimethanol) (PBS/CHDM) and poly(polybutylene succinate-co-diglycolic acid) (PBS/DGA) in mixed solvent of tetrahydrofuran (THF) and toluene was examined. Lipase was used as catalyst to degrade polymers with molecular weight of more than 100,000
Stephen C Yang et al.
Bioconjugate chemistry, 19(6), 1164-1169 (2008-05-27)
Acute inflammatory diseases are a major cause of death in the world, and effective treatments are greatly needed. Macrophages play a central role in causing acute inflammatory diseases, and there is currently great interest in developing drug delivery vehicles that
Pu Wang et al.
Biomaterials science, 6(5), 1262-1270 (2018-04-17)
One of the major challenges in anticancer therapy is the poor penetration of anticancer drugs into tumors, especially in solid tumors, resulting in decreased therapeutic efficacy in vivo. To solve some of these problems, in this study, a dual-responsive polymeric
Eric J Moskala
Medical device technology, 14(3), 12-16 (2003-06-07)
Gamma irradiation affects colour, most notably b, and total transmittance of all of the copolyesters used in this study. The changes in colour and total transmittance increase with increasing dose level and CHDM content of the copolyester. These changes are

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