126268
2,4-Dihydroxypyrimidine-5-carboxylic acid
95%
Synonym(s):
Isoorotic acid, Uracil-5-carboxylic acid
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About This Item
Empirical Formula (Hill Notation):
C5H4N2O4
CAS Number:
Molecular Weight:
156.10
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
245-947-2
MDL number:
Assay:
95%
Form:
powder
Quality Level
assay
95%
form
powder
mp
283 °C (dec.) (lit.)
functional group
carboxylic acid
SMILES string
OC(=O)C1=CNC(=O)NC1=O
InChI
1S/C5H4N2O4/c8-3-2(4(9)10)1-6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)
InChI key
ZXYAAVBXHKCJJB-UHFFFAOYSA-N
General description
2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. It has been used to synthesize N1-alkylated uracil derivatives.
Application
2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been used for the visual sensing of melamine (at parts-per-billion (ppb) level) by a highly sensitive analytical method based on Au nanoparticles.
ppe
Eyeshields, Gloves, type N95 (US)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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P M Shaffer et al.
Journal of bacteriology, 121(2), 648-655 (1975-02-01)
The experiments in this report involve the following series of reactions which were previously demonstrated with purified enzyme preparations from Neurospora crassa: thymidine a yields thymine ribonucleoside b yields thymine c yields 5-hydroxymethyluracil d yields 5-formyluracil e yields uracil-5-carboxylic acid
Raj Kumar Bera et al.
The Analyst, 136(8), 1644-1648 (2011-02-25)
A highly sensitive analytical method based on Au nanoparticles rationally tailored with recognition elements uracil-5-carboxylic acid (UCA) and 2,4,6-trinitrobenzenesulfonic acid (TNBS) for the visual sensing of melamine at the parts-per-billion (ppb) level is described. The tailored Au nanoparticles function as
Alessandro Accetta et al.
Journal of medicinal chemistry, 52(1), 87-94 (2008-12-17)
The synthesis of C5 linked uracil dimers was carried out according to a model developed in order to bind adenine in DNA. N1-Alkylated uracil derivatives were synthesized from isoorotic acid (uracil-5-carboxylic acid) or thymine. The carboxylic acid derivatives were condensed
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 126268-5G | 04061832912851 |