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128201

N-Ethyl-o-crotonotoluidide

97%

Synonym(s):

N-Ethyl-N-(2-methylphenyl)-2-butenamide, Crotamiton

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About This Item

Linear Formula:
CH3CH=CHCON(C2H5)C6H4CH3
CAS Number:
483-63-6
Molecular Weight:
203.28
NACRES:
NA.22
PubChem Substance ID:
24847834
UNSPSC Code:
12352100
EC Number:
207-596-3
MDL number:
MFCD00026989
Assay:
97%
Form:
solid
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description

predominantly trans

assay

97%

form

solid

refractive index

n20/D 1.54 (lit.)

bp

153-155 °C/13 mmHg (lit.)

solubility

ethanol: soluble, methanol: soluble

density

0.987 g/mL at 25 °C (lit.)

SMILES string

CCN(C(=O)\C=C\C)c1ccccc1C

InChI

1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3/b8-4+

InChI key

DNTGGZPQPQTDQF-XBXARRHUSA-N

Application

N-Ethyl-o-crotonotoluidide ( Crotamiton) was used to study the photocatalytic decomposition of crotamiton in aqueous solution using TiO2.
N-Ethyl-o-crotonotoluidide (Crotamiton) was used to treat scabies and various pruritic dermatoses.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
12204EU
10402BN
06028AW
04727CZ
35705DN

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The use of N-ethyl-o-crotonotoluidide in the treatment of scabies and various pruritic dermatoses.
M COUPERUS
The Journal of investigative dermatology, 13(1), 35-42 (1949-07-01)
Ahmed M Al-Arfaj et al.
The American journal of tropical medicine and hygiene, 76(5), 967-971 (2007-05-10)
A 31-year-old Saudi man was seen at an ear, nose, and throat clinic at Riyadh, Saudi Arabia, with bilateral itching in the external auditory canal. On otoscopic examination, the skin lining the ear canal was thickened with whitish sheets of
F Forton et al.
The British journal of dermatology, 138(3), 461-466 (1998-05-15)
A standardized skin surface biopsy was performed in 34 patients suffering from skin diseases with high Demodex folliculorum density (Dd) > 5D/cm2 before, during and after topical treatment. The patients were randomized into six comparable groups to study six topical
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Global Trade Item Number

SKUGTIN
CDS004264-100MG04061828913725
P8129-25MG04061832851303
128201-5G04061836682187