Key Documents

View All Documentation

128422

mono-Ethyl fumarate

Name: mono-Ethyl fumarate
Brand: ALDRICH

95%

Synonym(s):

Fumaric acid monoethyl ester, Monoethyl fumarate

Select a Size

Change View

About This Item

Linear Formula:

C₂H₅OCOCH=CHCOOH

CAS Number:

2459-05-4

Molecular Weight:

144.13

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24847858

EC Number:

219-544-7

Beilstein/REAXYS Number:

1723588

MDL number:

MFCD00002699

Assay:

95%

Form:

solid

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

100

assay

95%

form

solid

bp

147 °C/16 mmHg (lit.)

mp

66-68 °C (lit.)

SMILES string

CCOC(=O)\C=C\C(O)=O

InChI

1S/C6H8O4/c1-2-10-6(9)4-3-5(7)8/h3-4H,2H2,1H3,(H,7,8)/b4-3+

InChI key

XLYMOEINVGRTEX-ONEGZZNKSA-N

Description

Application

mono-Ethyl fumarate (fumaric acid monoethyl ester, monoethyl fumarate) was used in the preparation of photo-crosslinkable macromers. It was also used to synthesize Ugi/intramolecular Diels-Alder (IMDA) cycloaddition products.

Still not finding the right product?

Explore all of our products under mono-Ethyl fumarate

pictograms

GHS07

signalword

Warning

hcodes

H315,H317,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

An atom-economical approach to conformationally constrained tricyclic nitrogen heterocycles via sequential and tandem Ugi/intramolecular Diels-Alder reaction of pyrrole.

K Paulvannan

The Journal of organic chemistry, 69(4), 1207-1214 (2004-02-14)

An efficient approach to rigid tricyclic nitrogen heterocycles via sequential and tandem Ugi/intramolecular Diels-Alder (IMDA) cycloaddition of pyrrole is described. The one-pot Ugi four-component condensation (4CC) reaction was used as the key transformation to prepare trienes with a carboxamide substituent

Dimethylfumarate is an inhibitor of cytokine-induced E-selectin, VCAM-1, and ICAM-1 expression in human endothelial cells.

M Vandermeeren et al.

Biochemical and biophysical research communications, 234(1), 19-23 (1997-05-08)

Most studies on the antipsoriatic mode of action of dimethylfumarate focused on its antiproliferative effects in keratinocytes. Because inflammatory skin diseases are associated with an upregulation of endothelial cell adhesion molecules and because the presence of inflammatory cells in dermis

Treatment of severe psoriasis with fumaric acid esters: scientific background and guidelines for therapeutic use. The German Fumaric Acid Ester Consensus Conference.

U Mrowietz et al.

The British journal of dermatology, 141(3), 424-429 (1999-12-03)

Fumaric acid ester (FAE) therapy has proved to be safe and effective in patients with severe psoriasis vulgaris. This treatment was introduced nearly 30 years ago, but is only now gaining renewed interest among dermatologists. FAE therapy is licensed in

View All Related Papers

Global Trade Item Number

SKU	GTIN
128422-25G	04061831809763