135119
Triethyl phosphonoformate
98%
Synonym(s):
Ethyl diethoxyphospinylformate
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About This Item
Linear Formula:
(C2H5O)2P(O)COOC2H5
CAS Number:
Molecular Weight:
210.16
EC Number:
216-016-8
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1781949
MDL number:
InChI key
NOJFJZZMRDSOLM-UHFFFAOYSA-N
InChI
1S/C7H15O5P/c1-4-10-7(8)13(9,11-5-2)12-6-3/h4-6H2,1-3H3
SMILES string
CCOC(=O)P(=O)(OCC)OCC
assay
98%
bp
135 °C/12 mmHg (lit.)
density
1.11 g/mL at 25 °C (lit.)
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
Regulatory Information
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M Margalith et al.
Molecular and cellular biochemistry, 43(2), 97-103 (1982-03-19)
Three potential inhibitors of reverse transcriptase activities, phosphonoformate (PF), phosphonoacetate (PAA), and ethyl-diethyl phosphonoformate (Et-PF), were compared in this study. Only PF was found to inhibit the DNA polymerase activity of the purified reverse transcriptase of Moloney murine leukemia virus
Synthesis and antiviral properties of sterol phosphonoformates.
J M Bailey et al.
Biochemical Society transactions, 22(3), 353S-353S (1994-08-01)
Phosphonoformate inhibits synthesis of Epstein-Barr virus (EBV) capsid antigen and transformation of human cord blood lymphocytes by EBV.
M Margalith et al.
Virology, 102(1), 226-230 (1980-04-15)
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