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Merck
CN

139025

o-Arsanilic acid

98%

Synonym(s):

2-Aminobenzenearsonic acid

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About This Item

Linear Formula:
H2NC6H4AsO3H2
CAS Number:
Molecular Weight:
217.05
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
218-064-5
MDL number:
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assay

98%

form

powder

mp

154-155 °C (lit.)

solubility

1 M NH4OH: soluble 50 mg/mL, clear to turbid (orange-brown)

SMILES string

Nc1ccccc1[As](O)(O)=O

InChI

1S/C6H8AsNO3/c8-6-4-2-1-3-5(6)7(9,10)11/h1-4H,8H2,(H2,9,10,11)

InChI key

LQCOCUQCZYAYQK-UHFFFAOYSA-N

General description

o-Arsanilic acid on condensation reaction with methacryloyl chloride yields o-methacryloylaminophenylarsonic acid.

Application

o-Arsanilic acid was used in the determination of total arsenic in urine samples using nickel and palladium as matrix modifiers. It was used to study the inhibition of the binding of labeled anti-cross-reactive idiotype(CRI) preparations to a CRI+ hybridoma proteins by haptens in mice.


pictograms

Skull and crossbonesEnvironment

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Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

危险化学品

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Crystal and molecular structure of o-methacryloylaminophenylarsonic acid.
Percino MJ, et al.
Journal of Chemical Crystallography, 32(9), 307-314 (2002)
M J Nelles et al.
The Journal of experimental medicine, 154(6), 1752-1763 (1981-12-01)
Previous reports have shown the A/J anti-para-azophenylarsonate (anti-Ar) antibodies that share a major cross-reactive idiotype (CRI) comprise a family of closely related but nonidentical molecules. Serological studies with CRI+ monoclonal anti-Ar antibodies have suggested the presence of a conserved idiotypic
D E Nixon et al.
Clinical chemistry, 37(9), 1575-1579 (1991-09-01)
We evaluated the effectiveness of nickel and palladium with or without added potassium persulfate as matrix modifiers for the determination of total arsenic in urine. Complete recovery of pure aqueous solutions of As(III), As(V), cacodylic acid (DMA), monomethylarsinic acid (MMA)