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Merck
CN

14075

Sigma-Aldrich

Succinic semialdehyde solution

~15% in H2O (T)

Synonym(s):

4-Oxobutanoic acid, 4-Oxobutyric acid, Succinaldehydic acid, Succinic semialdehyde monomer

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About This Item

Linear Formula:
HCOCH2CH2COOH
CAS Number:
Molecular Weight:
102.09
Beilstein:
1745187
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
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concentration

~15% in H2O (T)

storage temp.

2-8°C

SMILES string

OC(=O)CCC=O

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Other Notes

Enzyme-catalyzed aldol reaction with DHAP; Substrate for succinic semialdehyde dehydrogenase

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Kathryn M McCulloch et al.
Biochemistry, 49(6), 1226-1235 (2010-01-27)
The gene identification and kinetic characterization of (E)-2-(acetamidomethylene)succinate (E-2AMS) hydrolase has recently been described. This enzyme catalyzes the final reaction in the degradation of vitamin B(6) and produces succinic semialdehyde, acetate, ammonia, and carbon dioxide from E-2AMS. The structure of
Natsumi Saito et al.
The Journal of biological chemistry, 284(24), 16442-16451 (2009-04-18)
The search for novel enzymes and enzymatic activities is important to map out all metabolic activities and reveal cellular metabolic processes in a more exhaustive manner. Here we present biochemical and physiological evidence for the function of the uncharacterized protein
W.-D. Fessner et al.
Angewandte Chemie (International Edition in English), 103, 596-596 (1991)
Baiqiang Yuan et al.
Journal of nutritional science and vitaminology, 54(3), 185-190 (2008-07-19)
We have found for the first time that a chromosomal gene, mlr6787, in Mesorhizobium loti encodes the pyridoxine degradative enzyme alpha-(N-acetylaminomethylene)succinic acid (AAMS) amidohydrolase. The recombinant enzyme expressed in Escherichia coli cells was homogeneously purified and characterized. The enzyme consisted
C P O'Byrne et al.
Journal of microbiological methods, 84(1), 137-139 (2010-11-04)
The GABase assay is widely used to rapidly and accurately quantify levels of extracellular γ-aminobutyric acid (GABA). Here we demonstrate a modification of this assay that enables quantification of intracellular GABA in bacterial cells. Cells are lysed by boiling and

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