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Merck
CN

141712

trans-1,2-Cyclohexanediol

98%

Synonym(s):

1,2-trans -Cyclohexanediol, 1,2-trans -Dihydroxycyclohexane, trans -2-Hydroxycyclohexanol

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About This Item

Linear Formula:
C6H10(OH)2
CAS Number:
Molecular Weight:
116.16
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
215-956-6
Beilstein/REAXYS Number:
3193810
MDL number:
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Product Name

trans-1,2-Cyclohexanediol, 98%

InChI key

PFURGBBHAOXLIO-PHDIDXHHSA-N

InChI

1S/C6H12O2/c7-5-3-1-2-4-6(5)8/h5-8H,1-4H2/t5-,6-/m1/s1

SMILES string

O[C@@H]1CCCC[C@H]1O

assay

98%

form

solid

mp

101-104 °C (lit.)

Quality Level

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Roosmarijn E Vandenbroucke et al.
Nucleic acids research, 35(12), e86-e86 (2007-06-23)
One of the major obstacles in non-viral gene transfer is the nuclear membrane. Attempts to improve the transport of DNA to the nucleus through the use of nuclear localization signals or importin-beta have achieved limited success. It has been proposed
Yoshihito Shiota et al.
Inorganic chemistry, 50(13), 6200-6209 (2011-06-04)
The catalytic conversion of 1,2-cyclohexanediol to adipic anhydride by Ru(IV)O(tpa) (tpa ═ tris(2-pyridylmethyl)amine) is discussed using density functional theory calculations. The whole reaction is divided into three steps: (1) formation of α-hydroxy cyclohexanone by dehydrogenation of cyclohexanediol, (2) formation of
J Mráz et al.
Scandinavian journal of work, environment & health, 25(3), 233-237 (1999-08-18)
This study explored the acute effect of ethanol (EtOH) on the urinary excretion of cyclohexanol (CH-ol), 1,2- and 1,4-cyclohexanediol (CH-diol), biomarkers of exposure to important solvents, and chemical intermediates cyclohexanone (CH-one), cyclohexane (CH) and cyclohexanol. Volunteers (5-8 in each group)
M Tanaka et al.
The Journal of organic chemistry, 66(8), 2667-2673 (2001-04-17)
Diastereoselective alkylation of ethyl 2-methyl- and/or 2-ethylacetoacetates using the (S,S)-cyclohexane-1,2-diol as an acetal chiral auxiliary afforded enol ethers (2a-f and 5a-f) of 92->95% de in 31-70% yields. Removal of the cyclohexane-1,2-diol with BF(3)-OEt(2) afforded beta-keto esters (3 and 6) bearing
David K Breslow et al.
The Journal of cell biology, 203(1), 129-147 (2013-10-09)
Specific proteins are concentrated within primary cilia, whereas others remain excluded. To understand the mechanistic basis of entry into cilia, we developed an in vitro assay using cells in which the plasma membrane was permeabilized, but the ciliary membrane was

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