14462
(−)-α-Bisabolol
≥93% (GC)
Synonym(s):
(-)-alpha-Bisabolol, (−)-6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol, Levomenol
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About This Item
Empirical Formula (Hill Notation):
C15H26O
CAS Number:
Molecular Weight:
222.37
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
208-205-9
MDL number:
Assay:
≥93% (GC)
Quality Level
assay
≥93% (GC)
optical activity
[α]/D -58±5°, neat
refractive index
n20/D 1.496
functional group
hydroxyl
SMILES string
C\C(C)=C\CC[C@](C)(O)[C@H]1CCC(C)=CC1
InChI
1S/C15H26O/c1-12(2)6-5-11-15(4,16)14-9-7-13(3)8-10-14/h6-7,14,16H,5,8-11H2,1-4H3/t14-,15+/m1/s1
InChI key
RGZSQWQPBWRIAQ-CABCVRRESA-N
General description
(-)-α-Bisabolol is the major constituent of essential oil from leaves of Hymenocrater yazdianus.
Application
(-)-α-Bisabolol was used to investigate the leishmanicidal and cytotoxic activity of essential oil of Vanillosmopsis arborea.
Biochem/physiol Actions
α-Bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias. It is the inhibitor of voltage-dependent Ca(2+) channels in tracheal smooth muscle preparations of rat. It also inhibits human and rat glioma cell growth and survival. It is a potential new therapeutic agent against leishmaniasis.
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hcodes
pcodes
Hazard Classifications
Aquatic Chronic 3
Storage Class
10 - Combustible liquids
flash_point_f
289.4 °F - closed cup
flash_point_c
143 °C - closed cup
ppe
Eyeshields, Gloves
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Shiva Masoudi et al.
Natural product communications, 7(1), 117-120 (2012-03-21)
Water-distilled essential oils from leaves of Hymenocrater yazdianus Rech.f., flowers of Stachys obtusicrena Boiss., and stems and flowers of Nepeta asterotricha Rech.f., which are endemic to Iran, were analyzed by GC and GC/MS. Fifty-five components of the leaf oil of
Aracélio Viana Colares et al.
Evidence-based complementary and alternative medicine : eCAM, 2013, 727042-727042 (2013-08-13)
The search for new immunopharmacological chemical agents to treat various diseases caused by bacteria, fungi, and protozoa, such as leishmaniasis, for example, has led to the exploration of potential products from plant species and their main active ingredients. Antimonial drugs
Orazio Taglialatela-Scafati et al.
Journal of natural products, 75(3), 453-458 (2012-02-09)
Apart from a large amount (ca. 2.0%) of α-bisabolol β-D-fucopyranoside (2a), the aerial parts of the Mediterranean weed Carthamus glaucus afforded an unusual triglyceride (E-2-crotonyl-1,3-distearolylglycerol, 7), two lipophilic flavonoids (6a,b), and a series of bisabolane fucopyranosides variously acylated on the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 14462-5ML | 04061838735768 |
| 14462-25ML | 04061838735751 |