146625
Bathocuproinedisulfonic acid disodium salt hydrate
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About This Item
Empirical Formula (Hill Notation):
C26H18N2Na2O6S2 · xH2O
CAS Number:
Molecular Weight:
564.54 (anhydrous basis)
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Form:
powder
form
powder
mp
300 °C (lit.)
functional group
phenyl, sulfonic acid
SMILES string
O.[Na+].[Na+].Cc1nc2c(ccc3c(-c4ccccc4)c(c(C)nc23)S([O-])(=O)=O)c(-c5ccccc5)c1S([O-])(=O)=O
InChI
1S/C26H20N2O6S2.2Na.H2O/c1-15-25(35(29,30)31)21(17-9-5-3-6-10-17)19-13-14-20-22(18-11-7-4-8-12-18)26(36(32,33)34)16(2)28-24(20)23(19)27-15;;;/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34);;;1H2/q;2*+1;/p-2
InChI key
ZAGWMJUGRCMNGX-UHFFFAOYSA-L
General description
Bathocuproine disulfonic acid (BCDS) is a stable Cu+ chelator and BCDS-Cu+ inhibits the HIV-1 wild type protease as well as a mutant HIV-1 protease lacking cysteine. It is an extracellular copper chelator.
Application
Bathocuproinedisulfonic acid disodium salt hydrate was used as chelator in electron spin resonance spin trapping technique to study free radical generation in rats with acute sodium formate poisoning. It was used as reagent for determination of Cu and Cu-protein complexes.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Suzie Kang et al.
International journal of molecular sciences, 21(20) (2020-10-22)
Copper is an essential metal ion that performs many physiological functions in living organisms. Deletion of Afmac1, which is a copper-responsive transcriptional activator in A. fumigatus, results in a growth defect on aspergillus minimal medium (AMM). Interestingly, we found that
D A Davis et al.
Archives of biochemistry and biophysics, 322(1), 127-134 (1995-09-10)
The protease encoded by the human immunodeficiency virus-1 (HIV-1) is essential for processing viral polyproteins which contain the enzymes and structural proteins required for the infectious virus. It was previously found that cupric chloride, in the presence of dithiothreitol or
The Geomagnetic Field Is a Contributing Factor for an Efficient Iron Uptake in Arabidopsis thaliana.
Monirul Islam et al.
Frontiers in plant science, 11, 325-325 (2020-05-07)
The Earth's magnetic field, defined as the geomagnetic field (GMF), is an unavoidable environmental factor for all living organisms. Variation in the GMF intensity was found to affect the content of some nutrients and their associated channels and transporters in
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 146625-1G | 04061838736994 |
| 146625-5G | 04061832418674 |