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149225

Dipropyl disulfide

Name: Dipropyl disulfide
Brand: ALDRICH

98%

Synonym(s):

Propyl disulfide

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About This Item

Linear Formula:

CH₃CH₂CH₂SSCH₂CH₂CH₃

CAS Number:

629-19-6

Molecular Weight:

150.31

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24848938

EC Number:

211-079-8

Beilstein/REAXYS Number:

969200

MDL number:

MFCD00009378

Assay:

98%

Form:

liquid

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Properties

Quality Level

100

assay

98%

form

liquid

refractive index

n20/D 1.497 (lit.)

bp

195-196 °C (lit.)

mp

−86 °C (lit.)

density

0.96 g/mL at 25 °C (lit.)

functional group

disulfide

SMILES string

CCCSSCCC

InChI

1S/C6H14S2/c1-3-5-7-8-6-4-2/h3-6H2,1-2H3

InChI key

ALVPFGSHPUPROW-UHFFFAOYSA-N

Description

General description

Dipropyl disulfide (DPDS) was an efficient scavenger of reactive oxygen species (ROS) at a lower concentration in both HL-60 and HepG2 cells. It prevents the oxidative DNA damage caused by N-nitrosopiperidine (NPIP) and N-nitrosodibutylamine (NDBA).

pictograms

GHS07,GHS09

signalword

Warning

hcodes

H315,H319,H335,H411

pcodes

P261 - P264 - P271 - P273 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

147.2 °F - closed cup

flash_point_c

64 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Metabolism of dipropyl disulfide by rat liver phase I and phase II enzymes and by isolated perfused rat liver.

C Teyssier et al.

Drug metabolism and disposition: the biological fate of chemicals, 28(6), 648-654 (2000-05-23)

The metabolism of dipropyl disulfide (DPDS), an Allium sulfur compound, was investigated in rat liver cell subfractions and in an isolated perfused rat liver. DPDS is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. The contribution of cytochrome P450 enzymes

A model system study of the inhibition of heterocyclic aromatic amine formation by organosulfur compounds.

Han-Seung Shin et al.

Journal of agricultural and food chemistry, 50(26), 7684-7690 (2002-12-12)

Organosulfur compounds and sodium bisulfite significantly inhibited (P < 0.05) heterocyclic aromatic amine (HAA) formation in model systems containing phenylalanine, creatinine, and glucose. There was, however, no inhibition by the same compounds in a model system containing only phenylalanine and

Effects of oil-soluble organosulfur compounds from garlic on doxorubicin-induced lipid peroxidation.

C Dwivedi et al.

Anti-cancer drugs, 9(3), 291-294 (1998-06-13)

Clinical efficacy of doxorubicin is compromised due to free radical generation leading to cardiac toxicity. Oil-soluble organosulfur compounds, diallyl sulfide (DAS), diallyl disulfide (DADS), dipropyl sulfide (DPS) and dipropyl disulfide (DPDS), present in garlic were examined for their antiperoxidant effects.

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Global Trade Item Number

SKU	GTIN
1644003-750MG	04061833020531
PHR3248-1G	04065267005508
149225-25G	04061838738264