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Merck
CN

150568

(−)-Glutathione, oxidized

Synonym(s):

L-Glutathione oxidized, GSSG, Glutathiol

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About This Item

Linear Formula:
[HO2CCH(NH2)CH2CH2CONHCH(CONHCH2CO2H)CH2S-]2
CAS Number:
Molecular Weight:
612.63
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
1718700
MDL number:
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SMILES string

[H][C@](N)(CCC(=O)N[C@@]([H])(CSSC[C@]([H])(NC(=O)CC[C@]([H])(N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1

InChI key

YPZRWBKMTBYPTK-BJDJZHNGSA-N

optical activity

[α]20/D -92.0 to -106.0°, c = 2% in H2O

impurities

≤6% water (Karl Fischer)

mp

178 °C (dec.) (lit.)

storage temp.

2-8°C

Application

Hydrogen acceptor in the enzymic determination of NADP and NADPH.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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The Journal of Organic Chemistry, 58, 4144-4144 (1993)
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(3), 906-913 (2013-01-18)
The accumulation of TDP-43 (transactive response DNA-binding protein 43) and its 25 kDa C-terminal fragment (TDP-25) is a hallmark of several neurodegenerative disorders, including frontotemporal lobar degeneration (FTLD-TDP) and amyotrophic lateral sclerosis (ALS). The majority of FTLD-TDP cases are due
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The in vitro and in vivo electrochemical detection of the reduced form of glutathione (L-γ-glutamyl-L-cysteinyl-glycine, GSH) using boron doped diamond (BDD) microelectrode for potential application in the assessment of cancerous tumors is presented. Accurate calibration curve for the determination of

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