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Merck
CN

15434

Boc-Tyr(tBu)-OH

≥99.0% (sum of enantiomers, TLC)

Synonym(s):

Boc-O-tert-butyl-L-tyrosine

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About This Item

Linear Formula:
(CH3)3COC6H4CH2CH(COOH)NHCOOC(CH3)3
CAS Number:
47375-34-8
Molecular Weight:
337.41
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
57647426
MDL number:
MFCD00065598
Beilstein/REAXYS Number:
4327336

Key Documents

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Product Name

Boc-Tyr(tBu)-OH, ≥99.0% (sum of enantiomers, TLC)

InChI

1S/C18H27NO5/c1-17(2,3)23-13-9-7-12(8-10-13)11-14(15(20)21)19-16(22)24-18(4,5)6/h7-10,14H,11H2,1-6H3,(H,19,22)(H,20,21)/t14-/m0/s1

SMILES string

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OC(C)(C)C)cc1)C(O)=O

InChI key

ZEQLLMOXFVKKCN-AWEZNQCLSA-N

assay

≥99.0% (sum of enantiomers, TLC)

optical activity

[α]20/D −15.0±1.0°, c = 1% in DMF

reaction suitability

reaction type: Boc solid-phase peptide synthesis

application(s)

peptide synthesis

storage temp.

2-8°C

Quality Level

100

Related Categories

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL6097
BCCG6080
BCBZ9750
BCBJ6066V
BCBM4533V

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Ria Schönauer et al.
Journal of peptide science : an official publication of the European Peptide Society, 21(12), 905-912 (2016-01-16)
The human adrenomedullin (ADM) is a 52 amino acid peptide hormone belonging to the calcitonin family of peptides, which plays a major role in the development and regulation of cardiovascular and lymphatic systems. For potential use in clinical applications, we
Genevra Kuziel et al.
Cancers, 12(8) (2020-08-01)
Obesity is correlated with breast tumor desmoplasia, leading to diminished chemotherapy response and disease-free survival. Obesity causes chronic, macrophage-driven inflammation within breast tissue, initiated by chemokine ligand 2 (CCL2) signaling from adipose stromal cells. To understand how CCL2-induced inflammation alters

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