Skip to Content
Merck
CN

15502

1-Boc-piperazine

≥98.0% (GC)

Synonym(s):

tert-Butyl piperazine-1-carboxylate

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C9H18N2O2
CAS Number:
57260-71-6
Molecular Weight:
186.25
NACRES:
NA.22
PubChem Substance ID:
57647377
eCl@ss:
32160406
UNSPSC Code:
12352100
MDL number:
MFCD00075265
Beilstein/REAXYS Number:
879985

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

1-Boc-piperazine, ≥98.0% (GC)

InChI

1S/C9H18N2O2/c1-9(2,3)13-8(12)11-6-4-10-5-7-11/h10H,4-7H2,1-3H3

SMILES string

CC(C)(C)OC(=O)N1CCNCC1

InChI key

CWXPZXBSDSIRCS-UHFFFAOYSA-N

assay

≥98.0% (GC)

form

solid

mp

43-47 °C (lit.)
43-47 °C

Quality Level

200

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

1-Boc-piperazine undergoes Buchwald-Hartwig amination with various aryl halides to form corresponding amine derivatives. It can be used to synthesize monosubstituted piperazine intermediates of many bioactive molecules and piperazine containing drug substances, such as trazodone.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
WXBF7472V
WXBF6566V
WXBF4774V
WXBF1810V
BCCJ4544

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Conformationally rigid derivatives of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin-1a receptors.
Jorgensen WT, et al.
European Journal of Medicinal Chemistry, 143, 1644-1656 (2018)
Discovery of 1-[2-(2, 4-dimethylphenylsulfanyl) phenyl] piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder.
Bang-Andersen B, et al.
Journal of Medicinal Chemistry, 54(9), 3206-3221 (2011)
Synthesis and dual D2 and 5-HT1A receptor binding affinities of 5-piperidinyl and 5-piperazinyl-1 H-benzo [d] imidazol-2 (3 H)-ones.
Ullah N
Journal of Enzyme Inhibition and Medicinal Chemistry, 29(2), 281-291 (2014)
Design and synthesis of new potent N, N-bis (arylalkyl) piperazine derivatives as multidrug resistance (MDR) reversing agents.
Dei S, et al.
European Journal of Medicinal Chemistry, 147, 7-20 (2018)
Efficient copper-catalyzed cross-coupling of 1-Boc-piperazine with aryl iodides and its application in the synthesis of trazodone.
Yong FF, et al.
Tetrahedron Letters, 54(39), 5332-5334 (2013)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service