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157872

1,3-Dithiane

Name: 1,3-Dithiane
Brand: ALDRICH

97%

Synonym(s):

m-Dithiane (7CI), m-Dithiane (8CI)

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About This Item

Empirical Formula (Hill Notation):

C₄H₈S₂

CAS Number:

505-23-7

Molecular Weight:

120.24

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24849705

EC Number:

208-006-7

Beilstein/REAXYS Number:

102534

MDL number:

MFCD00006654

Assay:

97%

Form:

solid

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Properties

Quality Level

100

assay

97%

form

solid

mp

52-54 °C (lit.)

functional group

thioether

SMILES string

C1CSCSC1

InChI

1S/C4H8S2/c1-2-5-4-6-3-1/h1-4H2

InChI key

WQADWIOXOXRPLN-UHFFFAOYSA-N

Description

General description

1,3-Dithiane, a protected formaldehyde anion equivalent, serves as useful labeled synthon.

Application

1,3-Dithiane was used as reagent for deoxygenation of sulfoxides to their corresponding sulfides.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

194.0 °F - closed cup

flash_point_c

90 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Synthesis of isotopically labeled 1,3-dithiane.

Rodolfo A Martinez et al.

Journal of labelled compounds & radiopharmaceuticals, 57(5), 338-341 (2014-05-28)

The 1,3-dithiane is a protected formaldehyde anion equivalent that could serve as a useful labeled synthon. We report a facile synthesis of 1,3-[2-(13)C]- and 1,3-[2-(13)C, 2-(2)H2]dithiane in two steps from [(13)C]- or [(13) C, (2)H3 ]methyl phenyl sulfoxide. We have

Mass-spectrometric analysis of agonist-induced retinoic acid receptor gamma conformational change.

Valerie J Peterson et al.

The Biochemical journal, 362(Pt 1), 173-181 (2002-02-07)

Apo and holo forms of retinoic acid receptors, and other nuclear receptors, display differential sensitivity to proteolytic digestion that likely reflects the distinct conformational states of the free and liganded forms of the receptor. We have developed a method for

Asymmetric synthesis of α-amino-1,3-dithianes via chiral N-phosphonyl imine-based Umpolung reaction without using chromatography and recrystallization.

Padmanabha V Kattamuri et al.

The Journal of organic chemistry, 76(8), 2792-2797 (2011-03-17)

A series of α-amino-1,3-dithianes have been synthesized via the asymmetric Umpolung reaction of 2-lithio-1,3-dithianes with chiral N-phosphonyl imines in good chemical yields (up to 82%) and good to excellent diastereoselectivities (>99:1). The manner by which chiral N-phosphonyl imines are slowly

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Global Trade Item Number

SKU	GTIN
157872-25G	04061838743671
157872-5G	04061833544655