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158259

O-Methyl-L-tyrosine

Name: <I>O</I>-Methyl-<SC>L</SC>-tyrosine
Brand: ALDRICH

98%

Synonym(s):

4-Methoxy-L-phenylalanine

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About This Item

Linear Formula:

CH₃OC₆H₄CH₂CH(NH₂)CO₂H

CAS Number:

6230-11-1

Molecular Weight:

195.22

UNSPSC Code:

12352200

NACRES:

NA.22

PubChem Substance ID:

24849727

EC Number:

228-333-9

Beilstein/REAXYS Number:

2212726

MDL number:

MFCD00002604

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Properties

assay

98%

optical activity

[α]25/D −7°, c = 0.5 in 1 M HCl

reaction suitability

reaction type: solution phase peptide synthesis

mp

259-261 °C (dec.) (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

COc1ccc(C[C@H](N)C(O)=O)cc1

InChI

1S/C10H13NO3/c1-14-8-4-2-7(3-5-8)6-9(11)10(12)13/h2-5,9H,6,11H2,1H3,(H,12,13)/t9-/m0/s1

InChI key

GEYBMYRBIABFTA-VIFPVBQESA-N

Description

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Localized production of defence chemicals by intracellular symbionts of Haliclona sponges.

Ma Diarey Tianero et al.

Nature microbiology, 4(7), 1149-1159 (2019-04-03)

Marine sponges often house small-molecule-producing symbionts extracellularly in their mesohyl, providing the host with a means of chemical defence against predation and microbial infection. Here, we report an intriguing case of chemically mediated symbiosis between the renieramycin-containing sponge Haliclona sp.

Covalent adducts of melphalan with free amino acids and a model peptide studied by liquid chromatography/tandem mass spectrometry.

Debbie Dewaele et al.

Rapid communications in mass spectrometry : RCM, 30(6), 719-730 (2016-02-13)

Melphalan is a frequently used chemotherapeutical agent for the treatment of myeloma, breast cancer, ovarian cancer and sarcoma of soft tissue. A good knowledge of the reactivity of the drug toward the different amino acids, e.g. covalent adduct formation, is

Saturation Mutagenesis for Phenylalanine Ammonia Lyases of Enhanced Catalytic Properties.

Raluca Bianca Tomoiagă et al.

Biomolecules, 10(6) (2020-06-04)

Phenylalanine ammonia-lyases (PALs) are attractive biocatalysts for the stereoselective synthesis of non-natural phenylalanines. The rational design of PALs with extended substrate scope, highlighted the substrate specificity-modulator role of residue I460 of Petroselinum crispum PAL. Herein, saturation mutagenesis at key residue

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Global Trade Item Number

SKU	GTIN
158259-1G	04061838743831