158623
Phenoxyacetyl chloride
98%
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
C6H5OCH2COCl
CAS Number:
Molecular Weight:
170.59
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-862-4
Beilstein/REAXYS Number:
607585
MDL number:
Assay:
98%
Quality Level
assay
98%
refractive index
n20/D 1.534 (lit.)
bp
225-226 °C (lit.)
density
1.235 g/mL at 25 °C (lit.)
functional group
acyl chloride, phenoxy
SMILES string
ClC(=O)COc1ccccc1
InChI
1S/C8H7ClO2/c9-8(10)6-11-7-4-2-1-3-5-7/h1-5H,6H2
InChI key
PKUPAJQAJXVUEK-UHFFFAOYSA-N
Application
Phenoxyacetyl chloride was used in the synthesis of:
- series of macrocyclic bis-β-lactams
- 5-phenyl-6-epiphenoxymethylpenicillin benzyl ester
- N-protected guanosine derivatives, useful in RNA synthesis
- phenyloxyketene, for cycloaddition to imines leading to β-lactams
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
supp_hazards
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
H Vanderhaeghe et al.
Journal of medicinal chemistry, 18(5), 486-490 (1975-05-01)
Cycloaddition of azidoacetyl chloride to benzyl D-5,5-dimethyl-5-phenyl-2-thiazoline-4-carboxylate (1a) gave 5-phenyl-6alpha-azidopenicillanate (2a). By catalytic reduction of 2a and reaction with phenoxyacetyl chloride, 5-phenyl-6-epiphenoxymethylpenicillin benzyl ester (4a) was obtained. Oxidation of 4a gave the sulfoxide 6, which was isomerized in the presence
Tetrahedron Letters, 48, 1657-1657 (2007)
Yupeng Fan et al.
Organic letters, 6(15), 2555-2557 (2004-07-17)
[reaction: see text] The formation of a guanosine derivative silylated at both the O6 and amino groups was identified by (15)N NMR. This intermediate allows facile reaction with acetyl chloride or phenoxyacetyl chloride to give in high yield the corresponding
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 158623-10G | 04061838346285 |
| 158623-250G | 04061838744098 |
| 158623-50G | 04061838744104 |