161101
O,O′-Bis(trimethylsilyl)thymine
97%
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About This Item
Empirical Formula (Hill Notation):
C11H22N2O2Si2
CAS Number:
Molecular Weight:
270.48
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
Form:
solid
InChI
1S/C11H22N2O2Si2/c1-9-8-12-11(15-17(5,6)7)13-10(9)14-16(2,3)4/h8H,1-7H3
SMILES string
Cc1cnc(O[Si](C)(C)C)nc1O[Si](C)(C)C
InChI key
DRNUNECHVNIYHQ-UHFFFAOYSA-N
assay
97%
form
solid
bp
127-130 °C/18 mmHg (lit.)
mp
73-75 °C (lit.)
Quality Level
Application
O,O′-Bis(trimethylsilyl)thymine is a reactive intermediate for the preparation of nucleosides.
wgk
WGK 3
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Mark Lazari et al.
EJNMMI research, 3(1), 52-52 (2013-07-16)
Automated radiosynthesizers are vital for routine production of positron-emission tomography tracers to minimize radiation exposure to operators and to ensure reproducible synthesis yields. The recent trend in the synthesizer industry towards the use of disposable kits aims to simplify setup
Angewandte Chemie (International Edition in English), 8, 976-976 (1969)
Studies on synthetic nucleosides. I. Trimethylsilyl derivatives of pyrimidines and purines.
T Nishimura et al.
Chemical & pharmaceutical bulletin, 12(3), 352-356 (1964-03-01)
A NEW SYNTHETIC METHOD OF NUCLEOSIDES.
T NISHIMURA et al.
Chemical & pharmaceutical bulletin, 11, 1470-1472 (1963-11-01)
A general synthesis of pyrimidine nucleosides.
U Niedballa et al.
Angewandte Chemie (International ed. in English), 9(6), 461-462 (1970-06-01)
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