161136
3-Hydroxytyramine hydrobromide
99%
Synonym(s):
3,4-Dihydroxyphenethylamine hydrobromide, Dopamine hydrobromide
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About This Item
Linear Formula:
(HO)2C6H3CH2CH2NH2·HBr
CAS Number:
Molecular Weight:
234.09
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
211-436-8
MDL number:
InChI key
SGRSNYSOAPBTJP-UHFFFAOYSA-N
InChI
1S/C8H11NO2.BrH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H
SMILES string
Br.NCCc1ccc(O)c(O)c1
assay
99%
form
solid
mp
218-220 °C (lit.)
Application
3-Hydroxytyramine hydrobromide was used in the preparation of dopamine standards to measure the dopamine release and uptake in striatal brain slices from R6/1 HD model mice by fast-scan cyclic voltammetry. It was employed as internal standard in the determination of catecholamines in biological tissues by liquid chromatography.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Andrea N Ortiz et al.
Neuroscience letters, 492(1), 11-14 (2011-01-25)
Huntington's disease (HD) is a progressive, neurodegenerative movement disorder. Here, we used fast-scan cyclic voltammetry to measure dopamine release and uptake in striatal brain slices from R6/1 HD model mice. Peak dopamine release ([DA](max)) was significantly diminished in R6/1 mice
Determination of catecholamines in biological tissues by liquid chromatography with coulometric detection.
G de Saint Blanquat et al.
Journal of chromatography, 415(2), 388-392 (1987-04-10)
Azam Sargazi et al.
Colloids and surfaces. B, Biointerfaces, 171, 150-158 (2018-07-20)
Hyaluronic acid (HA) is increasingly investigated for biomedical applications such as regenerative medicine, aesthetic medicine, and drug delivery. Accordingly, conjugation of HA to PEGylated MNPs could increase the active targeting ability of nano-drug carriers toward CD44 receptors and be useful
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