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Merck
CN

176788

Sigma-Aldrich

Sodium deuteroxide solution

40 wt. % in D2O, 99 atom % D

Synonym(s):

Sodium deuteroxide solution, Sodium hydroxide-d

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About This Item

Linear Formula:
NaOD / D2O
CAS Number:
14014-06-3
Molecular Weight:
41.00
MDL number:
MFCD00037669
UNSPSC Code:
12352303
PubChem Substance ID:
24850600
NACRES:
NA.12

Key Documents

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isotopic purity

99 atom % D

Quality Level

200

form

liquid

concentration

40 wt. % in D2O

technique(s)

NMR: suitable

refractive index

n20/D 1.4196

mass shift

M+1

SMILES string

[Na+].[O-][2H]

InChI

1S/Na.H2O/h;1H2/q+1;/p-1/i/hD

InChI key

HEMHJVSKTPXQMS-DYCDLGHISA-M

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General description

Sodium deuteroxide solution 40 wt. % in D2O, 99 atom % D is a high-purity isotope product with a unique chemical profile that belongs to the class of isotopes. Produced by Sigma-Aldrich, we are committed to providing quality isotope products and a reliable supply chain. Available in industrial and pre-pack quantities.

Application

- NMR spectroscopy solvent for biomolecular structure analysis
- Neutron scattering experiments in materials science
- metabolic labeling studies in biological research
- Pharmaceutical formulation development

Features and Benefits

Features
- High reactivity for diverse applications
- Supports innovative pharmaceutical research
- Produces minimal by-products in reactions
- Suitable for various biological studies

Benefits
- Streamlines the pharmaceutical development process
- Enhances effectiveness of biological assays
- Improves accuracy in metabolic studies
- Supports advancements in personalized medicine

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Precautionary Statements

P280 - P305 + P351 + P338 - P310

Hazard Classifications

Skin Corr. 1A

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

美国出口管控产品
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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ0237
0000318475
MKCW8225
MKCW9674
MKCV8317

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Xiang Zhai et al.
Biochemistry, 53(21), 3486-3501 (2014-05-16)
Two mutations of the phosphodianion gripper loop in chicken muscle triosephosphate isomerase (cTIM) were examined: (1) the loop deletion mutant (LDM) formed by removal of residues 170-173 [Pompliano, D. L., et al. (1990) Biochemistry 29, 3186-3194] and (2) the loop
Dominique E Williams et al.
Chembiochem : a European journal of chemical biology, 16(10), 1474-1482 (2015-05-09)
With the goal of designing a lysosomal phospholipase mimic, we optimized experimental variables to enhance Ce(IV) -assisted hydrolysis of phosphatidylcholine (PC) liposomes. Our best result was obtained with the chelating agent bis-tris propane (BTP). Similar to the hydrolytic enzyme, Ce(IV)
Oliver Wahl et al.
Journal of pharmaceutical and biomedical analysis, 95, 1-10 (2014-03-19)
For the impurity profiling of the mucolytic and anti-inflammatory drug carbocisteine a high performance liquid chromatographic (HPLC) method using corona charged aerosol detection (CAD) was developed and fully validated following the ICH guideline Q2(R1). The response was linear (R²>0.995) over

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