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176974

2,4-Dihydroxypyridine

97%

Synonym(s):

2,4-Pyridinediol, 3-Deazauracil, 4-Hydroxy-2-pyridone

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About This Item

Empirical Formula (Hill Notation):
C5H5NO2
CAS Number:
626-03-9
Molecular Weight:
111.10
EC Number:
210-924-8
UNSPSC Code:
12352100
PubChem Substance ID:
24850611
Beilstein/REAXYS Number:
108533
MDL number:
MFCD00006273
Assay:
97%
Form:
solid
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assay

97%

form

solid

mp

272-276 °C (lit.)

SMILES string

Oc1ccnc(O)c1

InChI

1S/C5H5NO2/c7-4-1-2-6-5(8)3-4/h1-3H,(H2,6,7,8)

InChI key

ZEZJPIDPVXJEME-UHFFFAOYSA-N

General description

2,4-Dihydroxypyridine (3-deazauracil) is a potent inhibitor of dihydrouracil dehydrogenase.

Application

2,4-Dihydroxypyridine (3-deazauracil) was used in the synthesis of diazaphenoxathiin skeleton.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF7518
BCBX5128
BCBM4305V
BCBJ0850V
1436174V

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Maria Teresa Cocco et al.
European journal of medicinal chemistry, 38(1), 37-47 (2003-02-21)
Bis(pyridyl)methane derivatives 5-40 were obtained from the reaction of 4-hydroxy-2-pyridones 3 and 4 with aldehydes. Compounds 5-40 were evaluated for cytotoxic activity against a panel of 60 human cancer cell lines by the National Cancer Institute and some of them
J Molgó et al.
Journal de pharmacologie, 16 Suppl 2, 109-144 (1985-01-01)
In this review the effects of aminopyridines and chemically related compounds are documented in an attempt to analyse the mechanism underlying their presynaptic actions at the vertebrate neuromuscular junction. Aminopyridines and related compounds are of particular interest because they greatly
K T Lin et al.
Therapeutic drug monitoring, 5(4), 491-496 (1983-01-01)
A rapid and simple procedure for liquid chromatographic analysis of plasma 3-deazauridine (3-DU), an antineoplastic agent, was developed. The plasma was extracted with methanolic silver acetate to remove interfering ultraviolet-absorbing materials and the 3-DU partially purified on a small anion
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Global Trade Item Number

SKUGTIN
176974-1G04061826731970
176974-5G04061838753113