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178330

4-Amino-1-butanol

98%

Synonym(s):

4-Hydroxybutylamine

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About This Item

Linear Formula:
H2N(CH2)4OH
CAS Number:
13325-10-5
Molecular Weight:
89.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24850731
EC Number:
236-364-4
Beilstein/REAXYS Number:
1731411
MDL number:
MFCD00008230
Assay:
98%
Form:
liquid
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Quality Level

200

assay

98%

form

liquid

refractive index

n20/D ~1.462 (lit.)

bp

206 °C (lit.)

mp

16-18 °C (lit.)

density

0.967 g/mL at 25 °C (lit.)

functional group

amine, hydroxyl

SMILES string

NCCCCO

InChI

1S/C4H11NO/c5-3-1-2-4-6/h6H,1-5H2

InChI key

BLFRQYKZFKYQLO-UHFFFAOYSA-N

Application

4-Amino-1-butanol was used in the synthesis of cyclic amines.
4-Amino-1-butanol was used:
  • As a linker in the synthesis of highly branched poly(β-amino esters)(HPAEs) for gene delivery.
  • As a side chain to modulate antimicrobial and hemolytic activities of copolymers.
  • In the total synthesis of (+)-fawcettimine,(+)-fawcettidine, and (−)-lycojapodine A.

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pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB5643
STBL2230
BCBQ8586V
STBK4078
STBK2726

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Christopher L Grigsby et al.
Scientific reports, 3, 3155-3155 (2013-11-07)
As the designs of polymer systems used to deliver nucleic acids continue to evolve, it is becoming increasingly apparent that the basic bulk manufacturing techniques of the past will be insufficient to produce polymer-nucleic acid nanocomplexes that possess the uniformity
Highly branched poly (β-amino esters): Synthesis and application in gene delivery.
Cutlar L, et al.
Biomacromolecules, 16(9), 2609-2617 (2015)
Synthesis of cyclic amines and their alkyl derivatives from amino alcohols over supported copper catalysts.
Applied Catalysis, 53(1), 107-115 (1989)
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Global Trade Item Number

SKUGTIN
178330-1G04061838753724
178330-5G04061838753731