178470
4-(Trifluoromethyl)phenol
97%
Synonym(s):
α,α,α-Trifluoro-p-cresol, 4-Hydroxybenzotrifluoride
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Linear Formula:
CF3C6H4OH
CAS Number:
Molecular Weight:
162.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-945-7
Beilstein/REAXYS Number:
1637019
MDL number:
Assay:
97%
Form:
liquid
InChI key
BAYGVMXZJBFEMB-UHFFFAOYSA-N
InChI
1S/C7H5F3O/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4,11H
SMILES string
Oc1ccc(cc1)C(F)(F)F
assay
97%
form
liquid
mp
45-47 °C (lit.)
functional group
fluoro
storage temp.
2-8°C
Related Categories
General description
4-(Trifluoromethyl)phenol molecule, bound at the active site of H61T (His-61→Thr) mutant, shows strong density.
4-(Trifluoromethyl)phenol also known as p-trifluoromethylphenol, is used in synthesis of polymers and monomers.
4-(Trifluoromethyl)phenol also known as p-trifluoromethylphenol, is used in synthesis of polymers and monomers.
Application
4-(Trifluoromethyl)phenol (4-hydroxybenzotrifluoride) was used in the synthesis of diaryl ether.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Sol. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
183.2 °F - closed cup
flash_point_c
84 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Jin-Kyun Lee et al.
Chemical communications (Cambridge, England), (39)(39), 4780-4782 (2008-10-03)
A high yielding, batch mode synthesis of diaryl ethers and sulfides by an S(N)Ar fluoride-mediated process in scCO(2) has been developed; the use of a polymer-supported imidazolium fluoride reagent in batch mode led to the development of a fixed-bed continuous
B van de Wier et al.
Chemico-biological interactions, 242, 139-144 (2015-10-03)
Cytochrome P450 2E1 (CYP2E1) expression and activity in the liver is associated with the degree of liver damage in patients with alcoholic steatohepatitis (ASH) as well as non-alcoholic steatohepatitis (NASH). CYP2E1 is known to generate reactive oxygen species, which leads
M W Fraaije et al.
The Journal of biological chemistry, 275(49), 38654-38658 (2000-09-14)
Vanillyl-alcohol oxidase (VAO) is member of a newly recognized flavoprotein family of structurally related oxidoreductases. The enzyme contains a covalently linked FAD cofactor. To study the mechanism of flavinylation we have created a design point mutation (His-61 --> Thr). In
Selina Tisler et al.
Environmental science & technology, 53(13), 7400-7409 (2019-05-29)
The present study investigates the transformation of the antidepressant fluoxetine (FLX) by photo- and biodegradation and shows similarities and differences in transformation products (TPs). TPs were identified using LC-high-resolution mass spectrometry with positive and negative electrospray ionization. In a sunlight
D C Thompson et al.
Chemico-biological interactions, 126(1), 1-14 (2000-05-29)
4-Trifluoromethylphenol (4-TFMP) was cytotoxic to precision-cut rat liver slices as indicated by loss of intracellular potassium. Intracellular glutathione levels decreased and fluoride ion levels increased in a time and concentration-dependent manner. The cytotoxicity of 4-TFMP did not appear to be
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service