17852
4-(Boc-amino)-1-methylpyrrole-2-carboxylic acid
≥99.0% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C11H16N2O4
CAS Number:
Molecular Weight:
240.26
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
4470648
MDL number:
SMILES string
Cn1cc(NC(=O)OC(C)(C)C)cc1C(O)=O
InChI
1S/C11H16N2O4/c1-11(2,3)17-10(16)12-7-5-8(9(14)15)13(4)6-7/h5-6H,1-4H3,(H,12,16)(H,14,15)
InChI key
GOLAEMFBWAIGRX-UHFFFAOYSA-N
assay
≥99.0% (HPLC)
form
solid
mp
156-160 °C (dec.)
application(s)
peptide synthesis
Other Notes
Unnatural amino acid for preparing heteroaromatic oligoamides for regulating gen expression in biotechnology
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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E.E. Baird et al.
Journal of the American Chemical Society, 118, 6141-6141 (1996)
S White et al.
Nature, 391(6666), 468-471 (1998-02-14)
The design of synthetic ligands that read the information stored in the DNA double helix has been a long-standing goal at the interface of chemistry and biology. Cell-permeable small molecules that target predetermined DNA sequences offer a potential approach for
Karine Nozeret et al.
Biochimie, 149, 122-134 (2018-04-08)
Pericentromeric heterochromatin plays important roles in controlling gene expression and cellular differentiation. Fluorescent pyrrole-imidazole polyamides targeting murine pericentromeric DNA (major satellites) can be used for the visualization of pericentromeric heterochromatin foci in live mouse cells. New derivatives targeting human repeated
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