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18055

4-Bromo-L-phenylalanine

≥98.0% (NT)

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About This Item

Empirical Formula (Hill Notation):
C9H10BrNO2
CAS Number:
24250-84-8
Molecular Weight:
244.09
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
57647705
MDL number:
MFCD00063062
Beilstein/REAXYS Number:
2212159
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assay

≥98.0% (NT)

form

solid

optical activity

[α]20/D −22.0±2°, c = 0.5% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

~265 °C (dec.)

application(s)

peptide synthesis

SMILES string

N[C@@H](Cc1ccc(Br)cc1)C(O)=O

InChI

1S/C9H10BrNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1

InChI key

PEMUHKUIQHFMTH-QMMMGPOBSA-N

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBD3303V
BCBN8376V
1365140
1383471
1335070

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Journal of the American Chemical Society, 128(36), 11778-11783 (2006-09-07)
Introduction of a yeast suppressor tRNA (ytRNA(Phe)(CUA)) and a mutant yeast phenylalanyl-tRNA synthetase (yPheRS (T415G)) into an Escherichia coli expression host allows in vivo incorporation of phenylalanine analogues into recombinant proteins in response to amber stop codons. However, high-fidelity incorporation
N Sharma et al.
FEBS letters, 467(1), 37-40 (2000-02-09)
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