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180629

Diphenyl diselenide

Name: Diphenyl diselenide
Brand: ALDRICH

98%

Synonym(s):

Phenyl diselenide

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About This Item

Linear Formula:

C₆H₅SeSeC₆H₅

CAS Number:

1666-13-3

Molecular Weight:

312.13

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24850881

EC Number:

216-780-2

Beilstein/REAXYS Number:

2047179

MDL number:

MFCD00003001

Assay:

98%

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Properties

Quality Level

100

assay

98%

impurities

<2% diphenyl selenide

mp

59-61 °C (lit.)

SMILES string

[Se]([Se]c1ccccc1)c2ccccc2

InChI

1S/C12H10Se2/c1-3-7-11(8-4-1)13-14-12-9-5-2-6-10-12/h1-10H

InChI key

YWWZCHLUQSHMCL-UHFFFAOYSA-N

Description

General description

Diphenyl Diselenide is an organo selenium compound that is an oxidized derivative of benzeneselenol. It is a source of phenylseleno radicals. it is reactive with a wide range of organic nucleophiles, electrophiles, and radicals.

Application

Diphenyl diselenide is used:In the synthesis of diaryl selenides bycross-coupling of aryl halides with diphenyl diselenide in presence of copperferrite nanoparticle catalyst.

Biochem/physiol Actions

Diphenyl diselenide inhibits δ-aminolevulinate dehydratase (δ-ALA-D) from brain, liver and kidney in vitro.

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pictograms

GHS06,GHS08,GHS09

signalword

Danger

hcodes

H301 + H331,H373,H410

pcodes

P260 - P264 - P273 - P301 + P310 - P304 + P340 + P311 - P314

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

危险化学品

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Diphenyl diselenide and diphenyl ditelluride differentially affect delta-aminolevulinate dehydratase from liver, kidney, and brain of mice.

E N Maciel et al.

Journal of biochemical and molecular toxicology, 14(6), 310-319 (2000-11-18)

In the present study, the inhibitory effect of diphenyl diselenide and diphenyl ditelluride after in vitro, acute (a single dose), or chronic exposure (14 doses) was examined in mice 24 hours after the last administration. In vitro, diphenyl diselenide, and

Protective effects of diphenyl diselenide in a mouse model of brain toxicity.

Viviane Glaser et al.

Chemico-biological interactions, 206(1), 18-26 (2013-08-21)

Interest in organoselenide chemistry and biochemistry has increased in the past three decades, mainly due to their chemical and biological activities. Here, we investigated the protective effect of the organic selenium compound diphenyl diselenide (PhSe)2 (5 μmol/kg), in a mouse

Cognitive effects of diphenyl diselenide and estradiol treatments in ovariectomized mice.

Juliana Trevisan da Rocha et al.

Neurobiology of learning and memory, 99, 17-24 (2012-10-23)

This study investigated the effects of co-administration of diphenyl diselenide [(PhSe)(2)] and 17β-estradiol (E(2)) on spatial reference, recognition, and working memories in ovariectomized (OVX) female mice. Sixty-day-old female adult Swiss mice were submitted to ovariectomy. From the 30th until 32nd

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Global Trade Item Number

SKU	GTIN
180629-100G	04061835554454
180629-25G	04061838754912
180629-5G	04061838754929