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189758

3-Nitrobenzamide

Name: 3-Nitrobenzamide
Brand: ALDRICH

98%

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About This Item

Linear Formula:

O₂NC₆H₄CONH₂

CAS Number:

645-09-0

Molecular Weight:

166.13

NACRES:

NA.22

PubChem Substance ID:

24851394

UNSPSC Code:

12352100

EC Number:

211-431-0

MDL number:

MFCD00007984

Assay:

98%

Form:

solid

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Properties

Quality Level

100

assay

98%

form

solid

mp

140-143 °C (lit.)

functional group

amide, nitro

SMILES string

NC(=O)c1cccc(c1)[N+]([O-])=O

InChI

1S/C7H6N2O3/c8-7(10)5-2-1-3-6(4-5)9(11)12/h1-4H,(H2,8,10)

InChI key

KWAYEPXDGHYGRW-UHFFFAOYSA-N

Description

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Novel inhibitors of poly(ADP-ribose) synthetase.

M R Purnell et al.

The Biochemical journal, 185(3), 775-777 (1980-03-01)

In a search for new inhibitors of the nuclear enzyme poly(ADP-ribose) synthetase, it was found that various benzamides substituted in the 3-position were the most inhibitory compounds found to date. Two of the benzamides, 3-aminobenzamide and 3-methoxybenzamide, were found to

Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis.

Y Uchigata et al.

The Journal of biological chemistry, 257(11), 6084-6088 (1982-06-10)

We have shown previously that alloxan and streptozotocin, two major diabetogenic agents, cause DNA strand breaks in rat pancreatic islets and stimulate nuclear poly(ADP-ribose) synthetase, thereby depleting intracellular NAD level and inhibiting proinsulin synthesis (Okamoto, H. (1981) Mol. Cell. Biochem.

Global Trade Item Number

SKU	GTIN
189758-25G	04061838759344