191558
4-Aminobenzyl alcohol
98%
Synonym(s):
4-(Hydroxymethyl)aniline
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About This Item
Linear Formula:
H2NC6H4CH2OH
CAS Number:
Molecular Weight:
123.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-767-5
Beilstein/REAXYS Number:
2078680
MDL number:
Assay:
98%
Product Name
4-Aminobenzyl alcohol, 98%
InChI key
AXKGIPZJYUNAIW-UHFFFAOYSA-N
InChI
1S/C7H9NO/c8-7-3-1-6(5-9)2-4-7/h1-4,9H,5,8H2
SMILES string
Nc1ccc(CO)cc1
assay
98%
mp
60-65 °C (lit.)
functional group
hydroxyl
storage temp.
2-8°C
Quality Level
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Application
4-Aminobenzyl alcohol can be used:
- In the synthesis of 4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutylamino}benzyl ester.
- As a reactant to synthesize cross-azo compounds and cathepsin B cleavable dipeptide linker.
- As a starting material to synthesize hydrogelators for drug delivery applications.
General description
4-Aminobenzyl alcohol is used as a starting material to synthesize other organic compounds.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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A novel 4-aminobenzyl ester-based carboxy-protecting group for synthesis of atypical peptides by Fmoc-But solid-phase chemistry.
Chan WC, et al.
Journal of the Chemical Society. Chemical Communications, 21, 2209-2210 (1995)
The rational design of a peptide-based hydrogel responsive to H 2 S
Peltier R, et al.
Chemical Communications (Cambridge, England), 51(97), 17273-17276 (2015)
Katarzyna Gorska et al.
Chemical communications (Cambridge, England), 47(15), 4364-4366 (2011-03-04)
Nucleic acid templated reactions have attracted significant attention for nucleic acid sensing. Herein we report a general design which extends the potential of nucleic acid templated reactions to unleash the function of a broad diversity of small molecules such as
Improved Methodology for the Synthesis of a Cathepsin B Cleavable Dipeptide Linker, Widely Used in Antibody-Drug Conjugate Research
Mondal D, et al.
Tetrahedron Letters, 59(40), 3594-3599 (2018)
Seung Woo Chung et al.
Biomaterials, 192, 109-117 (2018-11-18)
Despite the emergence of advanced therapeutics such as targeted therapy and immunotherapy in the modern oncology, cytotoxic chemotherapy still remains as the first-line treatment option in a wide range of cancers attributing to its potency. Many endeavors have been made
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