193666
Chloropentafluorobenzene
99%
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Linear Formula:
ClC6F5
CAS Number:
Molecular Weight:
202.51
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-450-6
Beilstein/REAXYS Number:
1819389
MDL number:
Assay:
99%
Form:
liquid
InChI key
KGCDGLXSBHJAHZ-UHFFFAOYSA-N
InChI
1S/C6ClF5/c7-1-2(8)4(10)6(12)5(11)3(1)9
SMILES string
Fc1c(F)c(F)c(Cl)c(F)c1F
assay
99%
form
liquid
Quality Level
bp
122-123 °C/750 mmHg (lit.)
density
1.568 g/mL at 25 °C (lit.)
functional group
chloro, fluoro
General description
Reaction between chloropentafluorobenzene and strong N-bases in polar aprotic solvents and in the presence of water has been investigated. Chloropentafluorobenzene on reaction with ammonia yields 4-chloro-2,3,5,6-tetrafluoroaniline and 2-chloro-3,4,5,6-tetrafluoroaniline.
Application
Chloropentafluorobenzene has been used in the preparation of:
- 1,2-difluoro-1,2-bis-(pentafluorophenyl)dichlorane via fluorination with elemental fluorine at 128°C
- 5-chloro-1-(difluorochloro)-2,3,4,5,6,6-hexafluoro-1,3-cyclohexadiene via reaction with chlorine trifluoride at −78°C
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Inhalation
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
ppe
Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
E R Kinkead et al.
Toxicology and industrial health, 6(6), 533-550 (1990-12-01)
Ten Fischer 344 rats and six B6C3F1 mice of each sex were exposed to air, 0.25, 0.80, or 2.50 mg chloropentafluorobenzene (CPFB)/liter of air for three weeks, excluding weekends. Exposure to 2.50 mg/liter caused a reduction in the growth rate
Catalytic and Noncatalytic Ammonolysis of Chloropentafluorobenzene.
Selivanova GA, et al.
Russ. J. Org. Chem., 37(3), 404-409 (2001)
Synthesis of 1, 2 difluoro-1, 2-bis (pentafluorophenyl) dichlorane.
Obaleye JA and Sams LC.
Journal of Fluorine Chemistry, 24(4), 413-418 (1984)
H J Clewell et al.
Risk analysis : an official publication of the Society for Risk Analysis, 14(3), 265-276 (1994-06-01)
Noncancer risk assessment traditionally relies on applied dose measures, such as concentration in inhaled air or in drinking water, to characterize no-effect levels or low-effect levels in animal experiments. Safety factors are then incorporated to address the uncertainties associated with
W D Crank et al.
Toxicology and industrial health, 8(1-2), 21-35 (1992-01-01)
Chloropentafluorobenzene (CPFB) has been proposed as an innocuous simulant for the uptake of toxic gases. Exposure to CPFB in a training exercise could be inferred afterwards from a measurement of CPFB in expired breath. To understand the relationship between exposure
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service