196479
2-Phenyl-4-quinolinecarboxylic acid
99%
Synonym(s):
2-Phenylcinchoninic acid, Cinchophen
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About This Item
Empirical Formula (Hill Notation):
C16H11NO2
CAS Number:
Molecular Weight:
249.26
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Quality Level
Assay
99%
form
powder
mp
214-215 °C (lit.)
solubility
alcohol: soluble 1g in 120ml(lit.)
chloroform: soluble 1g in 400ml(lit.)
diethyl ether: soluble 1g in 100ml(lit.)
water: insoluble(lit.)
SMILES string
OC(=O)c1cc(nc2ccccc12)-c3ccccc3
InChI
1S/C16H11NO2/c18-16(19)13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H,(H,18,19)
InChI key
YTRMTPPVNRALON-UHFFFAOYSA-N
Related Categories
General description
2-Phenyl-4-quinolinecarboxylic acid on reaction with 5-aryl-2,3-dihydro-2,3-furandiones yields β-aroylpyruvoyl hydrazide of 2-phenyl-4-quinolinecarboxylic acid.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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S G Krylova et al.
Eksperimental'naia i klinicheskaia farmakologiia, 63(2), 44-47 (2000-06-02)
Dry aspen bark extract exhibits pronounced antiulcerogenic activity as demonstrated by the results of experiments using the models of histamine and atophan induced ulcers and the ulceration model according to H. Shay. The gastroprotector activity is manifested by decreasing number
[Prevention of experimental atophan ulcers of the stomach and duodenum in dogs with the aid of novocaine injections].
V M CHERNOV et al.
Farmakologiia i toksikologiia, 25, 444-449 (1962-07-01)
Structure-action relationship among drugs acting on connective tissues (anti-rheumatic agents).
M W WHITEHOUSE
Nature, 194, 984-985 (1962-06-09)
[GASTRIC PEPSIN RESPONSE TO ACTH RELEASE AND PEPTIC ULCER].
K ISHIHARA
Rinsho geka. Journal of clinical surgery, 19, 161-166 (1964-02-01)
A Takahashi et al.
Journal of gastroenterology, 31(2), 153-160 (1996-04-01)
The contribution of granulocytes and their byproducts to acute gastric mucosal lesion (AGML) is unclear. Our previous study showed that granulocytes produced O2- in the gastric mucosa of rats treated with 300 mg/kg of cinchophen (cinchophen ulcer, CU) and in
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