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Merck
CN

196479

2-Phenyl-4-quinolinecarboxylic acid

99%

Synonym(s):

2-Phenylcinchoninic acid, Cinchophen

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About This Item

Empirical Formula (Hill Notation):
C16H11NO2
CAS Number:
Molecular Weight:
249.26
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
205-067-1
MDL number:
Assay:
99%
Form:
powder
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InChI key

YTRMTPPVNRALON-UHFFFAOYSA-N

InChI

1S/C16H11NO2/c18-16(19)13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H,(H,18,19)

SMILES string

OC(=O)c1cc(nc2ccccc12)-c3ccccc3

assay

99%

form

powder

mp

214-215 °C (lit.)

solubility

alcohol: soluble 1g in 120ml(lit.), chloroform: soluble 1g in 400ml(lit.), diethyl ether: soluble 1g in 100ml(lit.), water: insoluble(lit.)

Quality Level

General description

2-Phenyl-4-quinolinecarboxylic acid on reaction with 5-aryl-2,3-dihydro-2,3-furandiones yields β-aroylpyruvoyl hydrazide of 2-phenyl-4-quinolinecarboxylic acid.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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[Gout].
Y OSHIMA
Naika. Internal medicine, 10, 1101-1102 (1962-12-01)
S G Krylova et al.
Eksperimental'naia i klinicheskaia farmakologiia, 63(2), 44-47 (2000-06-02)
Dry aspen bark extract exhibits pronounced antiulcerogenic activity as demonstrated by the results of experiments using the models of histamine and atophan induced ulcers and the ulceration model according to H. Shay. The gastroprotector activity is manifested by decreasing number
[Contributions to evaluation of the substances inhibiting inflammation].
F VARGA et al.
Acta physiologica Academiae Scientiarum Hungaricae, 23, 69-78 (1963-01-01)
[DISTRIBUTION AND CONTENT OF RIBONUCLEOPROTEINS IN THE SMALL INTESTINE MUCOUS MEMBRANE IN CHRONIC EXPERIMENTAL STOMACH ULCER IN DOGS].
S A DALIMOV et al.
Meditsinskii zhurnal Uzbekistana, 39, 50-53 (1963-08-01)
Amides and hydrazides of aroylpyrivic acids. Part 6 Synthesis and study of antiinflammatory and analgesic activity of ?-aroylpyruvoyl hydrazides of 2-methyl (phenyl)-4-quinolinecarboxylic acids.
Milyutin AV, et al.
Pharmaceutical Chemistry Journal, 32(8), 422-424 (1998)

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