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Sigma-Aldrich

2-(p-Chlorophenoxy)-2-methylpropionic acid

97%

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Synonym(s):
α-(p-Chlorophenoxy)isobutyric acid, Clofibric acid
Linear Formula:
ClC6H4OC(CH3)2CO2H
CAS Number:
882-09-7
Molecular Weight:
214.65
EC Number:
212-925-9
MDL number:
MFCD00004192
PubChem Substance ID:
24851846

Quality Level

200

Assay

97%

mp

120-122 °C (lit.)

SMILES string

CC(C)(Oc1ccc(Cl)cc1)C(O)=O

InChI

1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)

InChI key

TXCGAZHTZHNUAI-UHFFFAOYSA-N

Gene Information

human ... PPARA(5465) , PPARG(5468)
mouse ... Ppara(19013) , Pparg(19016)

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Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Manoharan Saravanan et al.
Journal of hazardous materials, 195, 188-194 (2011-09-03)
Investigation on the toxic effects of pharmaceutical drugs namely clofibric acid (CA) and diclofenac (DCF) were studied in a common carp Cyprinus carpio at different concentrations such as 1, 10 and 100 μg L(-1) for a short-term period of 96
Dong Qing Zhang et al.
Environmental science and pollution research international, 20(7), 4612-4620 (2013-01-01)
Pharmaceutical compounds are now considered as emerging contaminants of environmental concern. The overall objective of this study was to evaluate the uptake and translocation of clofibric acid (CA) by the macrophyte Scirpus validus growing hydroponically. A set of the three
Dong Qing Zhang et al.
Environmental pollution (Barking, Essex : 1987), 167, 124-131 (2012-05-09)
This study evaluated the effect of continuous and batch feeding on the removal of 8 pharmaceuticals (carbamazepine, naproxen, diclofenac, ibuprofen, caffeine, salicylic acid, ketoprofen and clofibric acid) from synthetic wastewater in mesocosm-scale constructed wetlands (CWs). Both loading modes were operated
Julia Martín et al.
Journal of environmental management, 102, 18-25 (2012-03-20)
In this work, the distribution and the ecotoxicological risk of sixteen pharmaceutically active compounds belonging to seven different therapeutic groups (five anti-inflammatory drugs, two antibiotics, an anti-epileptic drug, a β-blocker, a nervous stimulant, four estrogens and two lipid regulators) have
R Salgado et al.
Journal of hazardous materials, 241-242, 182-189 (2012-10-16)
Clofibric acid (CLF) is the pharmaceutically active metabolite of lipid regulators clofibrate, etofibrate and etofyllinclofibrate, and it is considered both environmentally persistent and refractory. This work studied the biotransformation of CLF in aerobic sequencing batch reactors (SBRs) with mixed microbial
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