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Merck
CN

19999

tert-Butyl hydroperoxide solution

packed in FEP bottles, ~5.5 M in nonane (over molecular sieve 4 Å)

Synonym(s):

1,1-Dimethylethyl hydroperoxide, 2-Hydroperoxy-2-methylpropane, TBHP

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About This Item

Linear Formula:
(CH3)3COOH
CAS Number:
Molecular Weight:
90.12
UNSPSC Code:
12352120
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1098280
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Product Name

tert-Butyl hydroperoxide solution, packed in FEP bottles, ~5.5 M in nonane (over molecular sieve 4 Å)

InChI

1S/C4H10O2/c1-4(2,3)6-5/h5H,1-3H3

SMILES string

CC(C)(C)OO

InChI key

CIHOLLKRGTVIJN-UHFFFAOYSA-N

form

liquid

quality

packed in FEP bottles

reaction suitability

reagent type: oxidant

concentration

~5.5 M in nonane (over molecular sieve 4 Å)

refractive index

n20/D 1.400

density

0.82 g/mL at 20 °C

functional group

hydroperoxide

storage temp.

2-8°C

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Other Notes

Safe and stable oxidant for the Sharpless epoxidation

Reactant also used as a redox initiator and oxidant

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Org. Perox. F - Skin Corr. 1C - Skin Sens. 1 - STOT SE 3

target_organs

Central nervous system, Respiratory system

Storage Class

5.2 - Organic peroxides and self-reacting hazardous materials

wgk

WGK 3

flash_point_f

84.2 °F - closed cup

flash_point_c

29 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
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K. Alagiri and K. R. Prabhu,
Tetrahedron, 67, 8544-8551 (2011)
X. Zhu, et al.,
Huaxue Xuebao, 69, 1107-1114 (2011)
B. Chaband, K.B. Sharpless
The Journal of Organic Chemistry, 44, 4202-4202 (1979)
T. Katsuki et al.
Org. React., 48, 1-1 (1996)
Ramya Sivangala Thandi et al.
Nature communications, 11(1), 3535-3535 (2020-07-17)
Macrophages are professional phagocytes known to play a vital role in controlling Mycobacterium tuberculosis (Mtb) infection and disease progression. Here we compare Mtb growth in mouse alveolar (AMs), peritoneal (PMs), and liver (Kupffer cells; KCs) macrophages and in bone marrow-derived monocytes (BDMs).

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