200522
Poly(ethylene-co-propylene-co-5-methylene-2-norbornene)
ethylene 70 wt. %
Synonym(s):
Ethylene-5-ethylidenenorbornene-propene copolymer
InChI
1S/C9H12.C3H6.C2H4/c1-2-8-5-7-3-4-9(8)6-7;1-3-2;1-2/h2-4,7,9H,5-6H2,1H3;3H,1H2,2H3;1-2H2/b8-2+;;
InChI key
MPXNNMASLYQCAH-SZPWSVBHSA-N
form
solid
composition
ethylene, 70 wt. %
viscosity
80, Mooney(lit.)
density
0.86 g/mL at 25 °C (lit.)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Chelsea L Dieck et al.
Cancer cell, 34(1), 136-147 (2018-07-11)
Activating mutations in the cytosolic 5'-nucleotidase II gene NT5C2 drive resistance to 6-mercaptopurine in acute lymphoblastic leukemia. Here we demonstrate that constitutively active NT5C2 mutations K359Q and L375F reconfigure the catalytic center for substrate access and catalysis in the absence
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