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About This Item
Empirical Formula (Hill Notation):
As2O3
CAS Number:
Molecular Weight:
197.84
UNSPSC Code:
12161600
eCl@ss:
38080102
PubChem Substance ID:
NACRES:
NA.22
EC Number:
215-481-4
MDL number:
Product Name
Arsenic(III) oxide, 99.995% trace metals basis
Quality Level
assay
99.995% trace metals basis
form
powder
reaction suitability
core: arsenic, reagent type: catalyst
SMILES string
O=[As]O[As]=O
InChI
1S/As2O3/c3-1-5-2-4
InChI key
IKWTVSLWAPBBKU-UHFFFAOYSA-N
General description
Arsenic(III) oxide (ATO) is an inorganic form of arsenic that is used as a therapeutic compound for treating patients with acute promyelocytic leukemia (APL). Many drug-delivery methods are currently being developed using nanotechnology to overcome its poor bioavailability due to rapid clearance from blood.
Application
- Electrochemical detection applications: A study on La-based perovskites incorporated with functionalized carbon nanofibers highlights the use of arsenic trioxide for the electrochemical detection of roxarsone in water and food samples, providing a method to improve safety and environmental monitoring (John Felix MA et al., 2024).
- Antiproliferative effects in cancer research: Research demonstrates the inhibitory effects of arsenic trioxide, combined with metformin, on KG1a cell proliferation, suggesting its potential utility in developing antineoplastic strategies (Huang-Li WH et al., 2024).
- Environmental remediation: A review on manganese oxide-based materials for arsenic removal discusses the application of arsenic trioxide in environmental remediation, focusing on the effectiveness and advancements in arsenic decontamination technologies (Younas M et al., 2024).
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1
target_organs
Respiratory system,Cardio-vascular system,Gastrointestinal tract
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
监管及禁止进口产品
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A facile route to core?shell nanoparticulate formation of arsenic trioxide for effective solid tumor treatment.
Zhang Z, et al.
Nanoscale, 8(7), 4373-4380 (2016)
Recent advances in arsenic trioxide encapsulated nanoparticles as drug delivery agents to solid cancers.
Akhtar A, et al.
Journal of biomedical research, 31(3), 177-177 (2017)
Silica nanovehicles endow arsenic trioxide with an ability to effectively treat cancer cells and solid tumors.
Zhao Z, et al.
Journal of Materials Chemistry, 2(37), 6313-6323 (2014)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 202673-5G | 04061838765154 |
| 202673-25G | 04061838765147 |



