206571
6-Methoxy-8-nitroquinoline
99%
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C10H8N2O3
CAS Number:
Molecular Weight:
204.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
201-633-7
MDL number:
Assay:
99%
Form:
powder
InChI key
MIMUSZHMZBJBPO-UHFFFAOYSA-N
InChI
1S/C10H8N2O3/c1-15-8-5-7-3-2-4-11-10(7)9(6-8)12(13)14/h2-6H,1H3
SMILES string
COc1cc([N+]([O-])=O)c2ncccc2c1
assay
99%
form
powder
mp
158-160 °C (lit.)
functional group
nitro
Application
6-Methoxy-8-nitroquinoline was used in the synthesis of:
- 6-methoxy-8-aminoquinoline, metabolite of primaquine
- 6-methoxy-8-hydroxylaminoquinoline
- 2-substituted/2,5-disubstituted-6-methoxy-8-nitroquinolines
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Suryanarayana Vangapandu et al.
Bioorganic & medicinal chemistry, 12(10), 2501-2508 (2004-04-28)
We report in vitro antimycobacterial properties of ring-substituted quinolines (series 1-4) constituting 56 analogues against drug-sensitive and drug-resistant M. tuberculosis H37Rv strains. The most effective compounds 2h (R1 = R2 = c-C6H11, R3 = NO2, series 1) and 13g (R1
L J Bolchoz et al.
The Journal of pharmacology and experimental therapeutics, 297(2), 509-515 (2001-04-17)
Primaquine is an important antimalarial agent because of its activity against exoerythrocytic forms of Plasmodium spp. However, methemoglobinemia and hemolytic anemia are dose-limiting side effects of primaquine therapy that limit its efficacy. These hemotoxicities are thought to be mediated by
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service