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Merck
CN

210358

Sigma-Aldrich

4-Chloro-N-methylaniline

97%

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About This Item

Linear Formula:
ClC6H4NHCH3
CAS Number:
Molecular Weight:
141.60
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
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Assay

97%

form

liquid

refractive index

n20/D 1.584 (lit.)

bp

239 °C (lit.)

density

1.169 g/mL at 25 °C (lit.)

SMILES string

CNc1ccc(Cl)cc1

InChI

1S/C7H8ClN/c1-9-7-4-2-6(8)3-5-7/h2-5,9H,1H3

InChI key

XCEYKKJMLOFDSS-UHFFFAOYSA-N

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 3 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

125.6 °F - closed cup

Flash Point(C)

52 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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S Cottrell et al.
Xenobiotica; the fate of foreign compounds in biological systems, 20(7), 711-726 (1990-07-01)
1. Because of the low concentration of cytochrome P-450 in avocado fruit, microsomal fractions were prepared using polyethylene glycol aggregation and low-speed centrifugation, thus avoiding the need for high-speed centrifugation of large volumes of post-mitochondrial supernatant. Recoveries of cytochrome P-450
Brian W Budzik et al.
Bioorganic & medicinal chemistry letters, 20(4), 1363-1367 (2010-01-26)
A series of 3-aryl-4-isoxazolecarboxamides identified from a high-throughput screening campaign as novel, potent agonists of the human TGR5 G-protein-coupled receptor is described. Many analogues were readily accessible via solution-phase synthesis which resulted in the rapid identification of key structure-activity relationships
C Varshneya et al.
Toxicology letters, 31(2), 107-111 (1986-05-01)
White leghorn cockerels were fed a diet containing 0, 400, 800 and 1600 ppm of malathion for 90 days. Malathion O,O-dimethyl S-(1,2-dicarbethoxy) ethyl phosphorodithioate) at 800 and 1600 ppm caused a significant decrease in body weights. There was a significant
M Weiner et al.
Drug metabolism and disposition: the biological fate of chemicals, 8(3), 139-142 (1980-05-01)
Hepatic metabolism of aniline, p-chloro-N-methylaniline, and aminopyrine was determined in control male, New Zealand White rabbits or those bearing VX2 carcinoma (a prostaglandin-secreting tumor). In addition, the levels of cyclic AMP and cyclic GMP in the liver and the concentration
A Usha Rani et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 75(5), 1523-1529 (2010-03-20)
In this work, the vibrational spectral analysis was carried out by using FT-IR and FT-Raman spectroscopy in the range 400-4000 and 50-3500cm(-1) respectively, for the title molecule. The structural and spectroscopic data of the molecule in the ground state were

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