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211370

Sulfamide

Name: Sulfamide
Brand: ALDRICH

99%

Synonym(s):

Imidosulfamic acid, Sulfamoylamine, Sulfonyl diamide, Sulfuryl amide, Sulfuryl diamide

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About This Item

Linear Formula:

(NH₂)₂SO₂

CAS Number:

7803-58-9

Molecular Weight:

96.11

NACRES:

NA.22

PubChem Substance ID:

24852683

UNSPSC Code:

12352100

EC Number:

232-262-9

MDL number:

MFCD00011606

Assay:

99%

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Properties

Quality Level

200

assay

99%

mp

90-92 °C (lit.)

solubility

water: soluble 50 mg/mL, clear, colorless to faintly yellow

density

1.611 g/mL at 25 °C (lit.)

SMILES string

NS(N)(=O)=O

InChI

1S/H4N2O2S/c1-5(2,3)4/h(H4,1,2,3,4)

InChI key

NVBFHJWHLNUMCV-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760)

Description

General description

Sulfamide, a polar aprotic solvent compatible with Grignard reagents, is used as a functional group in medicinal chemistry.

Application

Sulfamide was used in the synthesis of:

Schiff bases of the type ArCH=NSO₂NH₂
1H,3H-2,1,3-benzothiadiazin-4-one-2,2-dioxide (BTDD)
sulfamide analogs of oleoylethanolamide analogs in a study of PPARα activation.

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Anomeric effects in sulfamides

Eric H et al.

The Journal of Physical Chemistry A, 120, 3677-3682 (2016)

Sulfamides and sulfonamides as polar aprotic solvents

Herman R G et al.

The Journal of Organic Chemistry, 52, 479-483 (1987)

Carbonic anhydrase inhibitors: inhibition studies of a coral secretory isoform with inorganic anions.

Anthony Bertucci et al.

Bioorganic & medicinal chemistry letters, 19(3), 650-653 (2009-01-06)

The inhibition of a coral carbonic anhydrase (CA, EC 4.2.1.1) has been investigated with a series of inorganic anions such as halogenides, pseudohalogenides, bicarbonate, carbonate, nitrate, nitrite, hydrogen sulfide, bisulfite, perchlorate, sulfate. The full-length scleractinian coral Stylophora pistillata CA, STPCA

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Global Trade Item Number

SKU	GTIN
211370-25G	04061832418872
211370-5G	04061838771773