Skip to Content
Merck
CN

Key Documents

View All Documentation

214981

Diisobutylaluminum hydride solution

1.0 M in THF

Synonym(s):

DIBAL, DIBAL-H

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
[(CH3)2CHCH2]2AlH
CAS Number:
1191-15-7
Molecular Weight:
142.22
NACRES:
NA.22
PubChem Substance ID:
24852859
eCl@ss:
38120609
UNSPSC Code:
12352001
MDL number:
MFCD00008928
Beilstein/REAXYS Number:
4123663
Form:
liquid
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

form

liquid

Quality Segment

reaction suitability

reagent type: reductant

concentration

1.0 M in THF

bp

65 °C

density

0.866 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

CC(C)C[AlH]CC(C)C

InChI

1S/2C4H9.Al.H/c2*1-4(2)3;;/h2*4H,1H2,2-3H3;;

InChI key

AZWXAPCAJCYGIA-UHFFFAOYSA-N

Application

Diisobutylaluminum hydride solution (1M in THF) is a powerful reducing agent. It can be used in the following reactions:
  • Synthesis of trans-alkene isosteres of protected dipeptides.
  • To generate bis(1,5-cyclooctadiene)nickel(0) (Ni(cod)2) in situ, which can catalyze the conjugate addition of ethenyltributyltin to 2-propenal to form tert-butyldimethyl[((E)-1,4pentadienyl)oxy]silane.
  • Reduction of the arylpropiolate esters to give the corresponding propargyl alcohol.

Used in Pd-catalyzed reductive debromination of secondary alkyl bromides. O-Debenzylation and ring opening of perbenzylated furanosides. Convenient in situ generation of HZrCp2Cl from ZrCp2Cl2 and DIBAL-H.

Packaging

View returnable container options.

Still not finding the right product?

Explore all of our products under Diisobutylaluminum hydride solution

Signal Word

Danger

Target Organs

Central nervous system, Respiratory system

supp_hazards

EUH014,EUH019

Storage Class

4.2 - Pyrophoric and self-heating hazardous materials

Flash Point (°F)

1.4 °F - closed cup

Flash Point (°C)

-17 °C - closed cup

PPE (personal protective equipment)

Faceshields, Gloves, Goggles

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Skin Corr. 1B - STOT SE 3 - Water-react. 1

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library