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Merck
CN

218898

5-(Dimethylamino)-1-naphthalenesulfonamide

99%

Synonym(s):

DNSA, Dansyl amide

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About This Item

Linear Formula:
(CH3)2NC10H6SO2NH2
CAS Number:
Molecular Weight:
250.32
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
215-854-1
Beilstein/REAXYS Number:
2217203
MDL number:
Assay:
99%
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Quality Segment

assay

99%

mp

218-221 °C (lit.)

fluorescence

λex 280 nm; λem 470 nm (bound to carbon anhydrase), λem 580 in ethanol

functional group

amine

SMILES string

CN(C)c1cccc2c(cccc12)S(N)(=O)=O

InChI

1S/C12H14N2O2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3,(H2,13,15,16)

InChI key

TYNBFJJKZPTRKS-UHFFFAOYSA-N

Application

5-(Dimethylamino)-1-naphthalenesulfonamide (DNSA) was used as starting reagent in the synthesis of 2,6-disubstituted pyridines, 6-substituted 2,2′-bipyridines and 6,6′-disubstituted 2,2′-bipyridines. It was also used as fluorescent probe in the determination of concentration of human carbonic anhydrase II-DNSA in solutions.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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