Key Documents

View All Documentation

219428

4-Fluoroiodobenzene

Name: 4-Fluoroiodobenzene
Brand: ALDRICH

99%

Synonym(s):

1-Fluoro-4-iodobenzene, 1-Iodo-4-fluorobenzene, 4-Fluoro-1-iodobenzene, 4-Fluorophenyl iodide, 4-Iodo-1-fluorobenzene, 4-Iodofluorobenzene, p-Fluoroiodobenzene, p-Fluorophenyl iodide, p-Iodofluorobenzene

Select a Size

Change View

About This Item

Linear Formula:

FC₆H₄I

CAS Number:

352-34-1

Molecular Weight:

222.00

NACRES:

NA.22

PubChem Substance ID:

24853127

UNSPSC Code:

12352100

EC Number:

206-522-7

MDL number:

MFCD00001052

Assay:

99%

Form:

liquid

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

100

assay

99%

form

liquid

contains

copper as stabilizer

refractive index

n20/D 1.583 (lit.)

bp

182-184 °C (lit.)

mp

−20 °C (lit.)

density

1.925 g/mL at 25 °C (lit.)

functional group

fluoro, iodo

SMILES string

Fc1ccc(I)cc1

InChI

1S/C6H4FI/c7-5-1-3-6(8)4-2-5/h1-4H

InChI key

KGNQDBQYEBMPFZ-UHFFFAOYSA-N

Description

General description

4-[¹⁸F] Fluoroiodobenzene is a versatile building block in ¹⁸F radiochemistry and is used in various transition metal-mediated C-C and C-N cross-coupling reactions. Cross-coupling reaction of 4-fluoroiodobenzene with potassium pentafluorophenyltrifluoroborate in the presence of different palladium catalysts and silver oxide in toluene has been investigated.

Application

4-Fluoroiodobenzene was used in the preparation of fluorotriphenylene derivatives.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

154.4 °F - closed cup

flash_point_c

68 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Automated radiosynthesis of no-carrier-added 4-[18F]fluoroiodobenzene: a versatile building block in 18F radiochemistry.

Jenilee Dawn Way et al.

Journal of labelled compounds & radiopharmaceuticals, 57(2), 104-109 (2014-03-29)

4-[18F]Fluoroiodobenzene ([18F]FIB) is a versatile building block in 18F radiochemistry used in various transition metal-mediated C-C and C-N cross-coupling reactions and [18F]fluoroarylation reactions. Various synthesis routes have been described for the preparation of [18F]FIB. However, to date, no automated synthesis

Palladium-catalyzed carbopalladation and carbocyclization of arynes with aryl halides: a highly efficient route to functionalized triphenylenes.

Thiruvellore Thatai Jayanth et al.

Chemical communications (Cambridge, England), (8)(8), 894-896 (2006-02-16)

Highly substituted triphenylene derivatives were prepared in good yields via the palladium-catalyzed carbocyclization of arynes with aryl iodides.

The effect of N-heterocyclic carbene ligands in the palladium-catalyzed cross-coupling reaction of K [C6F5BF3] with aryl iodides and aryl bromides.

Adonin NY, et al.

Tetrahedron, 64(25), 5920-5924 (2008)

View All Related Papers

Global Trade Item Number

SKU	GTIN
219428-5G	04061838775962
219428-50G	04061837082917