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Merck
CN

225517

Methoxylamine hydrochloride solution

25-30 wt. % in H2O

Synonym(s):

O-Methylhydroxylamine hydrochloride

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About This Item

Linear Formula:
CH3ONH2 · HCl
CAS Number:
593-56-6
Molecular Weight:
83.52
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24853502
MDL number:
MFCD00012951
Beilstein/REAXYS Number:
3589723
Form:
liquid

Key Documents

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InChI

1S/CH5NO.ClH/c1-3-2;/h2H2,1H3;1H

SMILES string

Cl[H].CON

InChI key

XNXVOSBNFZWHBV-UHFFFAOYSA-N

form

liquid

concentration

25-30 wt. % in H2O

refractive index

n20/D 1.4021

solubility

alcohol: soluble(lit.), water: soluble(lit.)

density

1.1 g/mL at 25 °C

Quality Level

100

Application

Methoxylamine hydrochloride was used as an derivatization agent during the structural investigation of novel epoxyisoprostane phospholipid in mildly oxidized low density lipoprotien.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Skin Corr. 1 - Skin Sens. 1 - STOT RE 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
STBF1292V
10916DQ
05814CI
04807CQ
2205AM

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A D Watson et al.
The Journal of biological chemistry, 274(35), 24787-24798 (1999-08-24)
One of the earliest steps in the development of the atherosclerotic lesion is the accumulation of monocyte/macrophages within the vessel wall. Oxidized lipids present in minimally modified-low density lipoproteins (MM-LDL) contribute to this process by activating endothelial cells to express
Eva M Goellner et al.
Cancer research, 71(6), 2308-2317 (2011-03-17)
Glioblastoma multiforme (GBM) is a devastating brain tumor with poor prognosis and low median survival time. Standard treatment includes radiation and chemotherapy with the DNA alkylating agent temozolomide (TMZ). However, a large percentage of tumors are resistant to the cytotoxic
Timothy J Kinsella
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(6), 1853-1859 (2009-02-26)
DNA damage processing by mismatch repair (MMR) and/or base excision repair (BER) can determine the therapeutic index following treatment of human cancers using radiation therapy and several classes of chemotherapy drugs. Over the last decade, basic and translational cancer research
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Oxidative DNA damage has been implicated in a number of central nervous system pathologies. The base excision repair (BER) pathway is one of the most important cellular protection mechanisms that respond to oxidative DNA damage. Human apurinic (apyrimidinic) endonuclease/redox effector
April M Luke et al.
Mutation research, 694(1-2), 65-71 (2010-09-21)
Single strand breaks (SSBs) are one of the most frequent DNA lesions caused by endogenous and exogenous agents. The most utilized alkaline-based assays for SSB detection frequently give false positive results due to the presence of alkali-labile sites that are
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