227811
2-Phenylhydroquinone
97%
Synonym(s):
2,5-Biphenyldiol, 2,5-Dihydroxybiphenyl
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About This Item
Linear Formula:
C6H5C6H3(OH)2
CAS Number:
Molecular Weight:
186.21
Beilstein:
1949429
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Quality Level
Assay
97%
mp
98-100 °C (lit.)
functional group
phenyl
SMILES string
Oc1ccc(O)c(c1)-c2ccccc2
InChI
1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H
InChI key
XCZKKZXWDBOGPA-UHFFFAOYSA-N
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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A C Lambert et al.
Mutation research, 322(4), 243-256 (1994-10-01)
o-Phenylphenol (OPP) and its sodium salt, sodium o-phenylphenate are broad spectrum fungicides and disinfectants with widespread usage. Both chemicals have been reported to induce cancer in the kidney and urinary bladder of Fischer 344 rats. Recently it has been proposed
S Tayama et al.
Mutation research, 259(1), 1-12 (1991-01-01)
The effects of cysteine and reduced glutathione (GSH) on the genotoxicity of o-phenylphenol (OPP) and its metabolites, phenylhydroquinone (PHQ) and phenylbenzoquinone (PBQ), were examined using the frequency of sister-chromatid exchanges (SCEs) and chromosome aberrations in CHO-K1 cells as parameters. Cytotoxic
S Tayama et al.
Mutation research, 324(3), 121-131 (1994-07-01)
Phenylhydroquinone (PHQ), a metabolite of o-phenylphenol (OPP), is easily autoxidized to phenylbenzoquinone (PBQ) via the semiquinone (phenylsemiquinone, PSQ) with concomitant production of superoxide anion radicals (O2-.). We have used scavengers of active oxygen species to examine whether or not O2-.
Y Nakagawa et al.
Xenobiotica; the fate of foreign compounds in biological systems, 23(2), 205-213 (1993-02-01)
1. The effects of diethyl maleate (DEM) on the cytotoxicity of phenyl-hydroquinone (PHQ) and other hydroquinones were studied in freshly isolated rat hepatocytes. 2. Addition of PHQ (0.5 or 0.75 mM) to hepatocytes resulted in dose-dependent cell death accompanied by
E S Kwok et al.
Chemical research in toxicology, 10(7), 742-749 (1997-07-01)
o-Phenylphenol (OPP) and its sodium salt (SOPP) are broad spectrum fungicides and antibacterials to which humans are frequently exposed. Both OPP and SOPP have been found to cause cancer in the urinary bladder of male F344 rats at high doses
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