229261
6,7-Dimethoxy-2-tetralone
97%
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About This Item
Empirical Formula (Hill Notation):
C12H14O3
CAS Number:
Molecular Weight:
206.24
UNSPSC Code:
12352100
PubChem Substance ID:
MDL number:
SMILES string
COc1cc2CCC(=O)Cc2cc1OC
assay
97%
mp
87-89 °C (lit.)
Gene Information
human ... CYP2A6(1548)
mouse ... Cyp2a5(13087)
Application
For enamine preparation and elaboration to dopamine agonists.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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W K Brewster et al.
Journal of medicinal chemistry, 33(6), 1756-1764 (1990-06-01)
trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenan thridine (4a, dihydrexidine) has been found to be a highly potent and selective agonist of the dopamine D1 receptor in rat brain. Dihydrexidine had an EC50 of approximately 70 nM in activating dopamine-sensitive rat striatal adenylate cyclase and a
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