23021
2-(2-Chloroethoxy)tetrahydro-2H-pyran
≥97.0%
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About This Item
Empirical Formula (Hill Notation):
C7H13ClO2
CAS Number:
Molecular Weight:
164.63
PubChem Substance ID:
UNSPSC Code:
12352100
Beilstein/REAXYS Number:
1280441
MDL number:
SMILES string
ClCCOC1CCCCO1
InChI
1S/C7H13ClO2/c8-4-6-10-7-3-1-2-5-9-7/h7H,1-6H2
InChI key
ZVVQFPGYDBUGQB-UHFFFAOYSA-N
assay
≥97.0%
refractive index
n20/D 1.459
bp
80 °C/8 mmHg (lit.)
density
1.115 g/mL at 20 °C (lit.)
General description
2-(2-Chloroethoxy)tetrahydro-2H-pyran is a building block for introducing a protected 2-hydroxyethyl group.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
149.0 °F - closed cup
flash_point_c
65 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
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H.G. Lohr et al.
Chemische Berichte, 118, 914-914 (1985)
Michael Klein et al.
PloS one, 6(6), e20789-e20789 (2011-06-24)
Highly selective, cell-permeable and fast-acting inhibitors of individual kinases are sought-after as tools for studying the cellular function of kinases in real time. A combination of small molecule synthesis and protein mutagenesis, identified a highly potent inhibitor (1-Isopropyl-3-(phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine) of a
B. Son et al.
Synthesis, 776-776 (1984)
H Ikuta et al.
Journal of medicinal chemistry, 30(11), 1995-1998 (1987-11-01)
A series of 3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-ones was synthesized and evaluated as candidate antiinflammatory/analgesic agents as well as dual inhibitors of prostaglandin and leukotriene synthesis. Some compounds that showed dual inhibitory activity were found to possess equipotent antiinflammatory activities to indomethacin, with reduced
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