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Merck
CN

230235

Diphenylphosphinic chloride

98%, liquid

Synonym(s):

Diphenylchlorophosphine oxide, Diphenylphosphinic acid chloride, Diphenylphosphinoyl chloride, Diphenylphosphinyl chloride, Diphenylphosphorus oxychloride, Ph2POCl, Chlorodiphenylphosphine oxide

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About This Item

Linear Formula:
(C6H5)2P(O)Cl
CAS Number:
Molecular Weight:
236.63
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352002
EC Number:
216-107-2
MDL number:
Beilstein/REAXYS Number:
975191
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Product Name

Diphenylphosphinic chloride, 98%

InChI key

QPQGTZMAQRXCJW-UHFFFAOYSA-N

InChI

1S/C12H10ClOP/c13-15(14,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H

SMILES string

ClP(=O)(c1ccccc1)c2ccccc2

assay

98%

form

liquid

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling

refractive index

n20/D 1.609 (lit.)

bp

222 °C/16 mmHg (lit.)

density

1.24 g/mL at 25 °C (lit.)

storage temp.

2-8°C

Quality Level

Application

Diphenylphosphinic chloride (Ph2POCl) is widely used as a precursor to synthesize various chiral phosphine bidentate ligands for asymmetric synthesis, in addition to several peptide coupling agents.

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1A

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

78.8 °F - closed cup

flash_point_c

26 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
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Ramage, R.; Atrash, B. et al.
Journal of the Chemical Society. Perkin Transactions 1, 1617-1617 (1985)
Efficient syntheses of korupensamines A, B and michellamine B by asymmetric Suzuki-Miyaura coupling reactions.
Xu G, et al.
Journal of the American Chemical Society, 136(2), 570-573 (2013)
Kim, S.; Lee, P. H.; Lee, T. A. J.
Journal of the Chemical Society. Chemical Communications, 1242-1242 (1988)
Aboujaoude, E. E.; Lietje, S. et al.
Tetrahedron Letters, 26, 4435-4435 (1985)
Meifang Wang
Inorganic Chemistry, 33, 6, 1184-1187 (1994)

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