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Merck
CN

233463

Sigma-Aldrich

5-Methyl-2-thiouracil

98%

Synonym(s):

4-Hydroxy-2-mercapto-5-methylpyrimidine

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About This Item

Empirical Formula (Hill Notation):
C5H6N2OS
CAS Number:
Molecular Weight:
142.18
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
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Assay

98%

SMILES string

CC1=CNC(=S)NC1=O

InChI

1S/C5H6N2OS/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)

InChI key

ZLAQATDNGLKIEV-UHFFFAOYSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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D Daujotyte et al.
Nucleic acids symposium series, (44)(44), 271-272 (2003-08-09)
HhaI DNA methyltransferase flips the inner cytosine in the recognition sequence 5'-GCGC-3' out of the DNA helix and into the catalytic site for methylation. To identify intermediate states on the base-flipping pathway, affinity photo-crosslinking experiments were performed with synthetic dodecamer
Jesús Mendieta et al.
Biochemistry, 43(2), 405-414 (2004-01-14)
The structural changes taking place in the enzyme thymidine phosphorylase (TPase, also known as PD-ECGF) that are required to achieve catalytic competence upon binding thymidine and phosphate have been simulated by means of targeted molecular dynamics (tMD). The hinge regions
Erika Lattová et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 33(6), 1146-1156 (2020-01-08)
Lung adenocarcinoma (LAC) is the most common form of lung cancer that increases in non-smokers at younger age. Altered protein glycosylation is one of the hallmarks of malignancy, its role in cancer progression is still poorly understood. In this study
I V Kutyavin et al.
Biochemistry, 35(34), 11170-11176 (1996-08-27)
A pair of complementary oligodeoxynucleotides (ODNs) uniformly substituted with 2-amino-adenine (A') in place of adenine and 2-thiothymine (T') in place of thymine did not hybridize to each other but did form very stable hybrids with unmodified complementary ODNs. These unusual
Erim Besić et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 61(13-14), 2803-2808 (2005-09-17)
EPR spectroscopy was used to study the complex formed in crystals of 5-methyl-2-thiouracil (2-thiothymine) containing traces of copper. The copper impurities, originally present as Cu(I)-complex of 2-thiothymine in the lattice of 2-thiothymine, are transformed into paramagnetic Cu(II)-complex by ionizing radiation.

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