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Merck
CN

235113

Trimethylsilyl bromoacetate

98%

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About This Item

Linear Formula:
BrCH2CO2Si(CH3)3
CAS Number:
Molecular Weight:
211.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
242-165-3
Beilstein/REAXYS Number:
1927560
MDL number:
Assay:
98%
Form:
liquid
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vapor density

>1 (vs air)

Quality Segment

assay

98%

form

liquid

refractive index

n20/D 1.442 (lit.)

bp

57-58 °C/9 mmHg (lit.)

density

1.284 g/mL at 25 °C (lit.)

SMILES string

C[Si](C)(C)OC(=O)CBr

InChI

1S/C5H11BrO2Si/c1-9(2,3)8-5(7)4-6/h4H2,1-3H3

InChI key

ZCHHFMWUDHXPFN-UHFFFAOYSA-N

Application

Trimethylsilyl bromoacetate has been used:
  • in the preparation of new imidazolium salts functionalized with the trimethylsilyl ester group
  • as alkylating agent in the synthesis of succinate fragment of pantocin B (antibiotic natural product)
  • in the synthesis of taxol derivatives tethered at C2′ and C-7 to glutamate and folate


pictograms

FlameCorrosion

signalword

Danger

hcodes

Hazard Classifications

Flam. Liq. 3 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

116.6 °F - closed cup

flash_point_c

47 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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